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9QJZ

Crystal structure of ARC4 from human Tankyrase 2 in complex with phosphorylated peptide from human MDC1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Poly [ADP-ribose] polymerase tankyrase-2polymer16717995.32UniProt (Q9H2K2)
Pfam (PF12796)
Homo sapiens (human)ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,Protein poly-ADP-ribosyltransferase tankyrase-2,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-2,TANK2,Tankyrase-like protein,Tankyrase-related protein
2C, D
(C, D)
Mediator of DNA damage checkpoint protein 1polymer161870.72UniProt (Q14676)Homo sapiensNuclear factor with BRCT domains 1
3E, F, G, H
(A, B, C, D)
waterwater18.057Chemie (HOH)
Sequence modifications
A, B: 488 - 649 (UniProt: Q9H2K2)
PDBExternal DatabaseDetails
Gly 483-expression tag
Ala 484-expression tag
Met 485-expression tag
Gly 486-expression tag
Ser 487-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight39732.1
All*Total formula weight39732.1
*Water molecules are not included.

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PDB entries from 2025-12-03

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