9QJZ
Crystal structure of ARC4 from human Tankyrase 2 in complex with phosphorylated peptide from human MDC1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Poly [ADP-ribose] polymerase tankyrase-2 | polymer | 167 | 17995.3 | 2 | UniProt (Q9H2K2) Pfam (PF12796) | Homo sapiens (human) | ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,Protein poly-ADP-ribosyltransferase tankyrase-2,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-2,TANK2,Tankyrase-like protein,Tankyrase-related protein |
| 2 | C, D (C, D) | Mediator of DNA damage checkpoint protein 1 | polymer | 16 | 1870.7 | 2 | UniProt (Q14676) | Homo sapiens | Nuclear factor with BRCT domains 1 |
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 57 | Chemie (HOH) |
Sequence modifications
A, B: 488 - 649 (UniProt: Q9H2K2)
| PDB | External Database | Details |
|---|---|---|
| Gly 483 | - | expression tag |
| Ala 484 | - | expression tag |
| Met 485 | - | expression tag |
| Gly 486 | - | expression tag |
| Ser 487 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 39732.1 | |
| All* | Total formula weight | 39732.1 |






