9QJY

GABA-A receptor a2b3g2 + a2NB04(silent) + GABA

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	Gamma-aminobutyric acid receptor subunit alpha-2	polymer	354	40452.4	2	UniProt (P47869)	Homo sapiens (human)	GABA(A) receptor subunit alpha-2,GABAAR subunit alpha-2
2	B, E (B, E)	Gamma-aminobutyric acid receptor subunit beta-3,Soluble cytochrome b562	polymer	451	51615.1	2	UniProt (P28472) UniProt (P0ABE7)	Homo sapiens (human)	GABA(A) receptor subunit beta-3,GABAAR subunit beta-3,Cytochrome b-562
3	C (C)	Gamma-aminobutyric acid receptor subunit gamma-2	polymer	371	42798.9	1	UniProt (P18507)	Homo sapiens (human)	GABA(A) receptor subunit gamma-2,GABAAR subunit gamma-2
4	F, G (F, G)	a2NB04	polymer	138	15060.5	2		Lama glama
5	H (H)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1235.1	1	In PDB GlyTouCan (G55220VL)
6	I, L (J, O)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
7	J, M (K, P)	alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1073.0	2	In PDB GlyTouCan (G09724ZC)
8	K (M)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G22768VO)
9	N, Q (A, D)	GAMMA-AMINO-BUTANOIC ACID	non-polymer		103.1	2	Chemie (ABU) PubChem (119)
10	O, P, R (A, C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG) PubChem (24139)

Sequence modifications

A, D: 1 - 311 (UniProt: P47869)

PDB	External Database	Details
Ser 312	-	expression tag
Gln 313	-	expression tag
Pro 314	-	expression tag
Ala 315	-	expression tag
Arg 316	-	expression tag
Ala 317	-	expression tag
Ala 318	-	expression tag
Lys 388	-	expression tag
Ile 389	-	expression tag
Asp 390	-	expression tag
Arg 391	-	expression tag
Met 392	-	expression tag
Ser 393	-	expression tag
Arg 394	-	expression tag
Ile 395	-	expression tag
Val 396	-	expression tag
Phe 397	-	expression tag
Pro 398	-	expression tag
Val 399	-	expression tag
Leu 400	-	expression tag
Phe 401	-	expression tag
Gly 402	-	expression tag
Thr 403	-	expression tag
Phe 404	-	expression tag
Asn 405	-	expression tag
Leu 406	-	expression tag
Val 407	-	expression tag
Tyr 408	-	expression tag
Trp 409	-	expression tag
Ala 410	-	expression tag
Thr 411	-	expression tag
Tyr 412	-	expression tag
Leu 413	-	expression tag
Asn 414	-	expression tag
Arg 415	-	expression tag
Glu 416	-	expression tag
Pro 417	-	expression tag
Val 418	-	expression tag
Leu 419	-	expression tag
Gly 420	-	expression tag
Val 421	-	expression tag
Ser 422	-	expression tag
Pro 423	-	expression tag

B, E: 1 - 307 (UniProt: P28472)

PDB	External Database	Details
Ser 308	-	linker
Gln 308	-	linker
Pro 308	-	linker
Ala 308	-	linker
Gly 308	-	linker
Thr 308	-	linker

B, E: 308 - 312 (UniProt: P0ABE7)

PDB	External Database	Details
Trp 308	Met 29	conflict
Ile 312	His 124	conflict
Leu 312	Arg 128	conflict
Thr 312	-	expression tag
Gly 312	-	expression tag
Arg 419	-	expression tag
Ala 420	-	expression tag
Ala 421	-	expression tag
Ala 422	-	expression tag
Ile 423	-	expression tag
Asp 424	-	expression tag
Arg 425	-	expression tag
Trp 426	-	expression tag
Ser 427	-	expression tag
Arg 428	-	expression tag
Ile 429	-	expression tag
Val 430	-	expression tag
Phe 431	-	expression tag
Pro 432	-	expression tag
Phe 433	-	expression tag
Thr 434	-	expression tag
Phe 435	-	expression tag
Ser 436	-	expression tag
Leu 437	-	expression tag
Phe 438	-	expression tag
Asn 439	-	expression tag
Leu 440	-	expression tag
Val 441	-	expression tag
Tyr 442	-	expression tag
Trp 443	-	expression tag
Leu 444	-	expression tag
Tyr 445	-	expression tag
Tyr 446	-	expression tag
Val 447	-	expression tag
Asn 448	-	expression tag

C: 1 - 409 (UniProt: P18507)

PDB	External Database	Details
Thr 11	Ala 50	conflict
Ser 402	Asn 362	conflict
Gln 403	Arg 363	conflict
Pro 404	Lys 364	conflict
Ala 405	Pro 365	conflict
Arg 406	Ser 366	conflict
Ala 407	Lys 367	conflict
Ala 408	Asp 368	conflict
Met 410	-	expression tag
Asp 411	-	expression tag
Ser 412	-	expression tag
Tyr 413	-	expression tag
Ala 414	-	expression tag
Arg 415	-	expression tag
Ile 416	-	expression tag
Phe 417	-	expression tag
Phe 418	-	expression tag
Pro 419	-	expression tag
Thr 420	-	expression tag
Ala 421	-	expression tag
Phe 422	-	expression tag
Cys 423	-	expression tag
Leu 424	-	expression tag
Phe 425	-	expression tag
Asn 426	-	expression tag
Leu 427	-	expression tag
Val 428	-	expression tag
Tyr 429	-	expression tag
Trp 430	-	expression tag
Val 431	-	expression tag
Ser 432	-	expression tag
Tyr 433	-	expression tag
Leu 434	-	expression tag
Tyr 435	-	expression tag
Leu 436	-	expression tag
Gly 437	-	expression tag
Thr 438	-	expression tag
Gly 439	-	expression tag
Thr 440	-	expression tag
Gly 441	-	expression tag
Thr 442	-	expression tag
Glu 443	-	expression tag
Thr 444	-	expression tag
Ser 445	-	expression tag
Gln 446	-	expression tag
Val 447	-	expression tag
Ala 448	-	expression tag
Pro 449	-	expression tag
Ala 450	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	257055.0
Branched	Number of molecules	6
	Total formula weight	5140.7
Non-Polymers*	Number of molecules	5
	Total formula weight	869.9
All*	Total formula weight	263065.5

*Water molecules are not included.