9QJE
USP7 Covalently Bound to N-(6-Fluoro-3-nitropyridin-2-yl)-5-(1-methyl-1H-pyrazol-4-yl)isoquinolin-3-amine (GCL36, 7a) with Partial Occupancy
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ubiquitin carboxyl-terminal hydrolase 7 | polymer | 356 | 41205.5 | 2 | UniProt (Q93009) Pfam (PF00443) | Homo sapiens (human) | Deubiquitinating enzyme 7,Herpesvirus-associated ubiquitin-specific protease,Ubiquitin thioesterase 7,Ubiquitin-specific-processing protease 7 |
| 2 | C, J (A, B) | ~{N}-(3-nitropyridin-2-yl)isoquinolin-3-amine | non-polymer | 347.4 | 2 | Chemie (A1I71) | |||
| 3 | D, F, I (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | E, H (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 5 | G, K, L (A, B) | BROMIDE ION | non-polymer | 79.9 | 3 | Chemie (BR) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 45 | Chemie (HOH) |
Sequence modifications
A, B: 207 - 560 (UniProt: Q93009)
| PDB | External Database | Details |
|---|---|---|
| Gly 205 | - | expression tag |
| Gly 206 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82411.0 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1332.9 | |
| All* | Total formula weight | 83743.9 |
