Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (CA) | Eukaryotic translation initiation factor 6 | polymer | 245 | 26620.0 | 1 | UniProt (P56537) Pfam (PF01912) | Homo sapiens (human) | eIF-6,B(2)GCN homolog,B4 integrin interactor,CAB,p27(BBP) |
| 2 | B (CB) | Nucleolar GTP-binding protein 2 | polymer | 731 | 83796.1 | 1 | UniProt (Q13823) Pfam (PF08153) Pfam (PF01926) | Homo sapiens (human) | Autoantigen NGP-1 |
| 3 | C (CC) | Guanine nucleotide-binding protein-like 3 | polymer | 549 | 62098.2 | 1 | UniProt (Q9BVP2) Pfam (PF08701) Pfam (PF01926) | Homo sapiens (human) | E2-induced gene 3 protein,Novel nucleolar protein 47,NNP47,Nucleolar GTP-binding protein 3,Nucleostemin |
| 4 | D (CD) | GTP-binding protein 4 | polymer | 634 | 74107.8 | 1 | UniProt (Q9BZE4) Pfam (PF17835) Pfam (PF06858) Pfam (PF08155) | Homo sapiens (human) | Chronic renal failure gene protein,GTP-binding protein NGB,Nucleolar GTP-binding protein 1 |
| 5 | E (CE) | Protein LLP homolog | polymer | 129 | 15268.4 | 1 | UniProt (Q9BRT6) Pfam (PF10169) | Homo sapiens (human) | Protein LAPS18-like |
| 6 | F (CF) | mRNA turnover protein 4 homolog | polymer | 239 | 27602.5 | 1 | UniProt (Q9UKD2) Pfam (PF00466) Pfam (PF17777) | Homo sapiens (human) | Ribosome assembly factor MRTO4 |
| 7 | G (CG) | Notchless protein homolog 1 | polymer | 485 | 53329.1 | 1 | UniProt (Q9NVX2) Pfam (PF08154) Pfam (PF00400) | Homo sapiens (human) | |
| 8 | H (CH) | Ribosome biogenesis protein NSA2 homolog | polymer | 260 | 30136.7 | 1 | UniProt (O95478) Pfam (PF01201) | Homo sapiens (human) | Hairy cell leukemia protein 1,TGF-beta-inducible nuclear protein 1 |
| 9 | I (CI) | Probable ribosome biogenesis protein RLP24 | polymer | 163 | 19666.3 | 1 | UniProt (Q9UHA3) Pfam (PF01246) | Homo sapiens (human) | Ribosomal L24 domain-containing protein 1,Ribosomal protein L24-like |
| 10 | J (CJ) | Ribosome production factor 2 homolog | polymer | 306 | 35658.1 | 1 | UniProt (Q9H7B2) Pfam (PF04427) | Homo sapiens (human) | Brix domain-containing protein 1,Ribosome biogenesis protein RPF2 homolog |
| 11 | K (CK) | Ribosome biogenesis regulatory protein homolog | polymer | 365 | 41278.5 | 1 | UniProt (Q15050) Pfam (PF04939) | Homo sapiens (human) | |
| 12 | L (L7) | 5S rRNA | polymer | 121 | 38998.1 | 1 | GenBank (23898) | Homo sapiens (human) | |
| 13 | M (LA) | 60S ribosomal protein L8 | polymer | 257 | 28088.9 | 1 | UniProt (P62917) Pfam (PF00181) Pfam (PF03947) | Homo sapiens (human) | Large ribosomal subunit protein uL2 |
| 14 | N (LB) | 60S ribosomal protein L3 | polymer | 403 | 46211.1 | 1 | UniProt (P39023) Pfam (PF00297) | Homo sapiens (human) | HIV-1 TAR RNA-binding protein B,TARBP-B,Large ribosomal subunit protein uL3 |
| 15 | O (LC) | 60S ribosomal protein L4 | polymer | 427 | 47804.6 | 1 | UniProt (P36578) Pfam (PF00573) Pfam (PF14374) | Homo sapiens (human) | 60S ribosomal protein L1,Large ribosomal subunit protein uL4 |
| 16 | P (LD) | 60S ribosomal protein L5 | polymer | 297 | 34426.8 | 1 | UniProt (P46777) Pfam (PF17144) Pfam (PF14204) | Homo sapiens (human) | Large ribosomal subunit protein uL18 |
| 17 | Q (LE) | Large ribosomal subunit protein eL6 | polymer | 288 | 32810.2 | 1 | UniProt (Q02878) Pfam (PF03868) Pfam (PF01159) | Homo sapiens (human) | 60S ribosomal protein L6,Neoplasm-related protein C140,Tax-responsive enhancer element-binding protein 107,TaxREB107 |
| 18 | R (LF) | Large ribosomal subunit protein uL30 | polymer | 248 | 29291.0 | 1 | UniProt (P18124) Pfam (PF08079) Pfam (PF00327) | Homo sapiens (human) | 60S ribosomal protein L7 |
| 19 | S (LG) | 60S ribosomal protein L7a | polymer | 266 | 30061.8 | 1 | UniProt (P62424) Pfam (PF01248) | Homo sapiens (human) | Large ribosomal subunit protein eL8,PLA-X polypeptide,Surfeit locus protein 3 |
| 20 | T (LH) | 60S ribosomal protein L9 | polymer | 192 | 21899.5 | 1 | UniProt (P32969) Pfam (PF00347) | Homo sapiens (human) | Large ribosomal subunit protein uL6 |
| 21 | U (LJ) | 60S ribosomal protein L11 | polymer | 178 | 20288.5 | 1 | UniProt (P62913) Pfam (PF00281) Pfam (PF00673) | Homo sapiens (human) | CLL-associated antigen KW-12,Large ribosomal subunit protein uL5 |
| 22 | V (LL) | 60S ribosomal protein L13 | polymer | 211 | 24321.7 | 1 | UniProt (P26373) Pfam (PF01294) | Homo sapiens (human) | Breast basic conserved protein 1,Large ribosomal subunit protein eL13 |
| 23 | W (LM) | 60S ribosomal protein L14 | polymer | 215 | 23485.0 | 1 | UniProt (P50914) Pfam (PF01929) | Homo sapiens (human) | CAG-ISL 7,Large ribosomal subunit protein eL14 |
| 24 | X (LN) | 60S ribosomal protein L15 | polymer | 204 | 24207.3 | 1 | UniProt (P61313) Pfam (PF00827) | Homo sapiens (human) | Large ribosomal subunit protein eL15 |
| 25 | Y (LO) | 60S ribosomal protein L13a | polymer | 203 | 23633.4 | 1 | UniProt (P40429) Pfam (PF00572) | Homo sapiens (human) | 23 kDa highly basic protein,Large ribosomal subunit protein uL13 |
| 26 | Z (LP) | 60S ribosomal protein L17 | polymer | 184 | 21443.2 | 1 | UniProt (P18621) Pfam (PF00237) | Homo sapiens (human) | 60S ribosomal protein L23,Large ribosomal subunit protein uL22,PD-1 |
| 27 | AA (LQ) | 60S ribosomal protein L18 | polymer | 188 | 21687.7 | 1 | UniProt (Q07020) Pfam (PF17135) | Homo sapiens (human) | Large ribosomal subunit protein eL18 |
| 28 | BA (LR) | 60S ribosomal protein L19 | polymer | 196 | 23535.3 | 1 | UniProt (P84098) Pfam (PF01280) | Homo sapiens (human) | Large ribosomal subunit protein eL19 |
| 29 | CA (LS) | 60S ribosomal protein L18a | polymer | 176 | 20808.5 | 1 | UniProt (Q02543) Pfam (PF01775) | Homo sapiens (human) | Large ribosomal subunit protein eL20 |
| 30 | DA (LT) | 60S ribosomal protein L21 | polymer | 160 | 18610.0 | 1 | UniProt (P46778) Pfam (PF01157) | Homo sapiens (human) | Large ribosomal subunit protein eL21 |
| 31 | EA (LU) | 60S ribosomal protein L22 | polymer | 128 | 14813.0 | 1 | UniProt (P35268) Pfam (PF01776) | Homo sapiens (human) | EBER-associated protein,EAP,Epstein-Barr virus small RNA-associated protein,Heparin-binding protein HBp15,Large ribosomal subunit protein eL22 |
| 32 | FA (LV) | 60S ribosomal protein L23 | polymer | 140 | 14892.5 | 1 | UniProt (P62829) Pfam (PF00238) | Homo sapiens (human) | 60S ribosomal protein L17,Large ribosomal subunit protein uL14 |
| 33 | GA (LX) | 60S ribosomal protein L23a | polymer | 156 | 17740.2 | 1 | UniProt (P62750) Pfam (PF03939) Pfam (PF00276) | Homo sapiens (human) | Large ribosomal subunit protein uL23 |
| 34 | HA (LY) | 60S ribosomal protein L26 | polymer | 145 | 17303.4 | 1 | UniProt (P61254) Pfam (PF16906) Pfam (PF00467) | Homo sapiens (human) | Large ribosomal subunit protein uL24 |
| 35 | IA (LZ) | 60S ribosomal protein L27 | polymer | 136 | 15835.8 | 1 | UniProt (P61353) Pfam (PF00467) Pfam (PF01777) | Homo sapiens (human) | Large ribosomal subunit protein eL27 |
| 36 | JA (La) | 60S ribosomal protein L27a | polymer | 148 | 16604.5 | 1 | UniProt (P46776) Pfam (PF00828) | Homo sapiens (human) | Large ribosomal subunit protein uL15 |
| 37 | KA (Lc) | 60S ribosomal protein L30 | polymer | 115 | 12805.1 | 1 | UniProt (P62888) Pfam (PF01248) | Homo sapiens (human) | Large ribosomal subunit protein eL30 |
| 38 | LA (Ld) | 60S ribosomal protein L31 | polymer | 125 | 14494.9 | 1 | UniProt (P62899) Pfam (PF01198) | Homo sapiens (human) | Large ribosomal subunit protein eL31 |
| 39 | MA (Le) | 60S ribosomal protein L32 | polymer | 135 | 15898.9 | 1 | UniProt (P62910) Pfam (PF01655) | Homo sapiens (human) | Large ribosomal subunit protein eL32 |
| 40 | NA (Lf) | 60S ribosomal protein L35a | polymer | 110 | 12564.7 | 1 | UniProt (P18077) Pfam (PF01247) | Homo sapiens (human) | Cell growth-inhibiting gene 33 protein,Large ribosomal subunit protein eL33 |
| 41 | OA (Lg) | 60S ribosomal protein L34 | polymer | 117 | 13326.1 | 1 | UniProt (P49207) Pfam (PF01199) | Homo sapiens (human) | Large ribosomal subunit protein eL34 |
| 42 | PA (Lh) | 60S ribosomal protein L35 | polymer | 123 | 14593.6 | 1 | UniProt (P42766) Pfam (PF00831) | Homo sapiens (human) | Large ribosomal subunit protein uL29 |
| 43 | QA (Li) | 60S ribosomal protein L36 | polymer | 105 | 12290.9 | 1 | UniProt (Q9Y3U8) Pfam (PF01158) | Homo sapiens (human) | Large ribosomal subunit protein eL36 |
| 44 | RA (Lj) | Large ribosomal subunit protein eL37 | polymer | 97 | 11111.0 | 1 | UniProt (P61927) Pfam (PF01907) | Homo sapiens (human) | 60S ribosomal protein L37,G1.16 |
| 45 | SA (Lk) | 60S ribosomal protein L38 | polymer | 70 | 8238.9 | 1 | UniProt (P63173) Pfam (PF01781) | Homo sapiens (human) | Large ribosomal subunit protein eL38 |
| 46 | TA (Ll) | 60S ribosomal protein L39 | polymer | 51 | 6426.8 | 1 | UniProt (P62891) Pfam (PF00832) | Homo sapiens (human) | Large ribosomal subunit protein eL39 |
| 47 | UA (Lp) | 60S ribosomal protein L37a | polymer | 92 | 10299.4 | 1 | UniProt (P61513) Pfam (PF01780) | Homo sapiens (human) | Large ribosomal subunit protein eL43 |
| 48 | VA (Lr) | 60S ribosomal protein L28 | polymer | 137 | 15784.6 | 1 | UniProt (P46779) Pfam (PF01778) | Homo sapiens (human) | Large ribosomal subunit protein eL28 |
| 49 | WA (Lt) | Large ribosomal subunit protein uL11 | polymer | 165 | 17847.6 | 1 | UniProt (P30050) Pfam (PF03946) Pfam (PF00298) | Homo sapiens (human) | 60S ribosomal protein L12 |
| 50 | XA (L5) | 28S rRNA | polymer | 5070 | 1640222.1 | 1 | GenBank (NR_003287) | Homo sapiens (human) | |
| 51 | YA (L8) | 5.8S rRNA | polymer | 157 | 50449.8 | 1 | GenBank (555853) | Homo sapiens (human) | |
| 52 | ZA (CB) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 53 | AB (CD) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 54 | BB (CD) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 55 | CB, DB, EB, FB (CI, Lg, Lj, Lp) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
CG: 1 - 485 (UniProt: Q9NVX2)
| PDB | External Database | Details |
|---|---|---|
| Ala 85 | Glu 85 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 51 |
| Total formula weight | 2954718.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1252.3 | |
| All* | Total formula weight | 2955970.4 |
