9QIA
Structure of UBA6-UbDha-BIRC6 trapped ternary complex (cluster 2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 | polymer | 325 | 36834.7 | 1 | UniProt (Q9NR09) Pfam (PF00179) | Homo sapiens (human) | BIR repeat-containing ubiquitin-conjugating enzyme,BRUCE,Baculoviral IAP repeat-containing protein 6,Ubiquitin-conjugating BIR domain enzyme apollon,APOLLON |
| 2 | B (B) | Ubiquitin-like modifier-activating enzyme 6 | polymer | 1054 | 118250.8 | 1 | UniProt (A0AVT1) Pfam (PF00899) Pfam (PF16190) Pfam (PF16191) Pfam (PF10585) Pfam (PF09358) | Homo sapiens (human) | Ubiquitin-activating enzyme 6,Monocyte protein 4,MOP-4,Ubiquitin-activating enzyme E1-like protein 2,E1-L2 |
| 3 | C, D (C, E) | Polyubiquitin-C | polymer | 76 | 8590.9 | 2 | UniProt (P0CG48) Pfam (PF00240) | Homo sapiens (human) | |
| 4 | E (B) | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 1 | Chemie (IHP) | |||
| 5 | F (E) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) |
Sequence modifications
A: 4498 - 4820 (UniProt: Q9NR09)
B: 1 - 1052 (UniProt: A0AVT1)
C, E: 1 - 76 (UniProt: P0CG48)
| PDB | External Database | Details |
|---|---|---|
| Gly 4496 | - | expression tag |
| Pro 4497 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Ser 625 | Cys 625 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 76 | Gly 76 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 172267.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1007.3 | |
| All* | Total formula weight | 173274.5 |
