9QI6
Structure of I105R BlaC from Mycobacterium tuberculosis bound to the trans-enamine adduct of clavulanic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-lactamase | polymer | 265 | 28316.8 | 2 | UniProt (P0A5I7) Pfam (PF00144) Pfam (PF13354) UniProt (by SIFTS) (P9WKD3) | Mycobacterium tuberculosis | Ambler class A beta-lactamase |
| 2 | C, D, E, M, N (A, B) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
| 3 | F, J, K, O, P (A, B) | ACETATE ION | non-polymer | 59.0 | 5 | Chemie (ACT) | |||
| 4 | G, I, Q, R (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | H (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 6 | L, S (A, B) | (2E)-3-[(4-hydroxy-2-oxobutyl)amino]prop-2-enal | non-polymer | 157.2 | 2 | Chemie (ISS) | |||
| 7 | T, U (A, B) | water | water | 18.0 | 392 | Chemie (HOH) |
Sequence modifications
A, B: 28 - 293 (UniProt: P0A5I7)
| PDB | External Database | Details |
|---|---|---|
| Arg 105 | Ile 117 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56633.5 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1411.1 | |
| All* | Total formula weight | 58044.6 |
