9QI3
Crystal structure of I105Y/S130G double mutant of BlaC from Mycobacterium tuberculosis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-lactamase | polymer | 266 | 28349.8 | 2 | UniProt (P0A5I7) | Mycobacterium tuberculosis | Ambler class A beta-lactamase |
| 2 | C, E (A, B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 3 | D (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | F (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 694 | Chemie (HOH) |
Sequence modifications
A, B: 28 - 293 (UniProt: P0A5I7)
| PDB | External Database | Details |
|---|---|---|
| Gly 27 | - | expression tag |
| Tyr 105 | Ile 117 | engineered mutation |
| Gly 130 | Ser 142 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56699.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 275.6 | |
| All* | Total formula weight | 56975.1 |
