9QHM
Cryo-EM structure of mouse TRPM3 alpha 2 in complex with antagonist Ononetin
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | MKIAA1616 protein | polymer | 1409 | 161963.3 | 4 | UniProt (Q69ZE8) | Mus musculus (house mouse) | |
| 2 | E, L, P, S (A, B, C, D) | 1-[2,4-bis(oxidanyl)phenyl]-2-(4-methoxyphenyl)ethanone | non-polymer | 258.3 | 4 | Chemie (A1D6M) | |||
| 3 | F, H, Q, T (A, C, D) | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE | non-polymer | 705.0 | 4 | Chemie (3PH) PubChem (447938) PubChem (86641) PubChem (16211043) | |||
| 4 | G, I, J, K, M... (A, B, C) | (25R)-14beta,17beta-spirost-5-en-3beta-ol | non-polymer | 414.6 | 8 | Chemie (YUV) PubChem (16396446) PubChem (16401075) PubChem (16406275) PubChem (16728676) PubChem (16757860) PubChem (10536) PubChem (176519883) PubChem (99474) PubChem (23616930) PubChem (234096) PubChem (24884134) PubChem (24884135) PubChem (24884137) PubChem (441900) PubChem (1738097) PubChem (24884136) PubChem (24884133) PubChem (45048825) PubChem (45114483) PubChem (44135547) PubChem (44268241) PubChem (46783391) PubChem (44630243) PubChem (71216913) PubChem (52951873) PubChem (52987653) PubChem (53486205) PubChem (49853458) PubChem (57896252) PubChem (58638014) PubChem (58638021) PubChem (58676952) PubChem (59068525) PubChem (59552208) PubChem (69179427) PubChem (69645870) PubChem (70679525) PubChem (5315382) PubChem (5316916) PubChem (70832476) PubChem (68236207) PubChem (68607954) PubChem (6432492) PubChem (6708723) PubChem (91747775) PubChem (10287767) PubChem (10501952) PubChem (11258502) PubChem (11350521) PubChem (11486815) PubChem (11546125) PubChem (11589713) PubChem (11633030) PubChem (11990273) PubChem (12304505) PubChem (12304506) PubChem (90658110) PubChem (99565298) PubChem (99565183) PubChem (117604447) PubChem (117626572) PubChem (124748311) PubChem (124748317) PubChem (124897616) PubChem (124897023) PubChem (102204095) PubChem (126543496) PubChem (129010058) PubChem (10173204) PubChem (129225054) PubChem (11080192) PubChem (124356768) PubChem (124485504) PubChem (124488608) PubChem (124488609) PubChem (124748310) PubChem (124748313) PubChem (124748314) PubChem (124831663) PubChem (124897022) PubChem (124897024) PubChem (124897025) PubChem (124897617) PubChem (126543539) PubChem (129225057) PubChem (139492597) PubChem (132275123) PubChem (133688187) PubChem (162923162) PubChem (162923146) PubChem (162923164) PubChem (162923154) PubChem (162923166) PubChem (137704703) PubChem (138108501) PubChem (139292125) PubChem (141699348) PubChem (168313844) PubChem (153235819) PubChem (154828454) PubChem (157539200) PubChem (158867846) PubChem (162923147) PubChem (162923148) PubChem (162923149) PubChem (162923150) PubChem (162923151) PubChem (162923152) PubChem (162923153) PubChem (162923155) PubChem (162923156) PubChem (162923157) PubChem (162923158) PubChem (162923159) PubChem (162923160) PubChem (162923161) PubChem (162923163) PubChem (162923165) PubChem (162923167) PubChem (164072579) PubChem (168011989) PubChem (168012062) PubChem (168325882) PubChem (169447683) PubChem (171153578) PubChem (171363718) |
Sequence modifications
A, B, C, D: 2 - 1344 (UniProt: Q69ZE8)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Ser 1 | - | expression tag |
| Ala 1345 | - | expression tag |
| Leu 1346 | - | expression tag |
| Glu 1347 | - | expression tag |
| Val 1348 | - | expression tag |
| Leu 1349 | - | expression tag |
| Phe 1350 | - | expression tag |
| Gln 1351 | - | expression tag |
| Gly 1352 | - | expression tag |
| Pro 1353 | - | expression tag |
| Gln 1354 | - | expression tag |
| Gly 1355 | - | expression tag |
| Thr 1356 | - | expression tag |
| Glu 1357 | - | expression tag |
| Gln 1358 | - | expression tag |
| Lys 1359 | - | expression tag |
| Leu 1360 | - | expression tag |
| Ile 1361 | - | expression tag |
| Ser 1362 | - | expression tag |
| Glu 1363 | - | expression tag |
| Glu 1364 | - | expression tag |
| Asp 1365 | - | expression tag |
| Leu 1366 | - | expression tag |
| Arg 1367 | - | expression tag |
| Gly 1368 | - | expression tag |
| Ala 1369 | - | expression tag |
| Ser 1370 | - | expression tag |
| Met 1371 | - | expression tag |
| Asp 1372 | - | expression tag |
| Glu 1373 | - | expression tag |
| Lys 1374 | - | expression tag |
| Thr 1375 | - | expression tag |
| Thr 1376 | - | expression tag |
| Gly 1377 | - | expression tag |
| Trp 1378 | - | expression tag |
| Arg 1379 | - | expression tag |
| Gly 1380 | - | expression tag |
| Gly 1381 | - | expression tag |
| His 1382 | - | expression tag |
| Val 1383 | - | expression tag |
| Val 1384 | - | expression tag |
| Glu 1385 | - | expression tag |
| Gly 1386 | - | expression tag |
| Leu 1387 | - | expression tag |
| Ala 1388 | - | expression tag |
| Gly 1389 | - | expression tag |
| Glu 1390 | - | expression tag |
| Leu 1391 | - | expression tag |
| Glu 1392 | - | expression tag |
| Gln 1393 | - | expression tag |
| Leu 1394 | - | expression tag |
| Arg 1395 | - | expression tag |
| Ala 1396 | - | expression tag |
| Arg 1397 | - | expression tag |
| Leu 1398 | - | expression tag |
| Glu 1399 | - | expression tag |
| His 1400 | - | expression tag |
| His 1401 | - | expression tag |
| Pro 1402 | - | expression tag |
| Gln 1403 | - | expression tag |
| Gly 1404 | - | expression tag |
| Gln 1405 | - | expression tag |
| Arg 1406 | - | expression tag |
| Glu 1407 | - | expression tag |
| Pro 1408 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 647853.0 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 7170.0 | |
| All* | Total formula weight | 655023.0 |
