9QH5
Consensus structure of UBA6-UbDha-BIRC6 trapped ternary complex (doubly loaded)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 | polymer | 325 | 36834.7 | 1 | UniProt (Q9NR09) Pfam (PF00179) | Homo sapiens (human) | BIR repeat-containing ubiquitin-conjugating enzyme,BRUCE,Baculoviral IAP repeat-containing protein 6,Ubiquitin-conjugating BIR domain enzyme apollon,APOLLON |
| 2 | B (B) | Ubiquitin-like modifier-activating enzyme 6 | polymer | 1054 | 118250.8 | 1 | UniProt (A0AVT1) Pfam (PF00899) Pfam (PF16190) Pfam (PF16191) Pfam (PF10585) Pfam (PF09358) | Homo sapiens (human) | Ubiquitin-activating enzyme 6,Monocyte protein 4,MOP-4,Ubiquitin-activating enzyme E1-like protein 2,E1-L2 |
| 3 | C, D (C, E) | Polyubiquitin-C | polymer | 76 | 8590.9 | 2 | UniProt (P0CG48) Pfam (PF00240) | Homo sapiens (human) | |
| 4 | E (B) | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 1 | Chemie (IHP) | |||
| 5 | F (E) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (40467049) PubChem (40469468) PubChem (44348067) PubChem (45358029) PubChem (46874558) PubChem (40459109) PubChem (46875232) PubChem (177678969) PubChem (6083) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (1549371) PubChem (92144436) PubChem (224) PubChem (12358354) PubChem (34768) PubChem (83862) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (122197642) PubChem (5316444) PubChem (5742864) PubChem (12163610) PubChem (12358355) PubChem (162290139) PubChem (162946266) PubChem (171699505) |
Sequence modifications
A: 4498 - 4820 (UniProt: Q9NR09)
B: 1 - 1052 (UniProt: A0AVT1)
C, E: 1 - 76 (UniProt: P0CG48)
| PDB | External Database | Details |
|---|---|---|
| Gly 4496 | - | expression tag |
| Pro 4497 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Ser 625 | Cys 625 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 76 | Gly 76 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 172267.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1007.3 | |
| All* | Total formula weight | 173274.5 |
