9QGI

Structure of dUBA1-UbDha-dBIRC6 trapped ternary complex (Cluster 2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	BIR repeat containing ubiquitin-conjugating enzyme, isoform B	polymer	305	35565.3	1	UniProt (A0A0B4KG50) Pfam (PF00179)	Drosophila melanogaster (fruit fly)
2	B (B)	E1 ubiquitin-activating enzyme	polymer	1010	112045.2	1	UniProt (Q8T0L3) Pfam (PF00899) Pfam (PF16190) Pfam (PF16191) Pfam (PF10585) Pfam (PF09358)	Drosophila melanogaster (fruit fly)	Ubiquitin-activating enzyme E1
3	C, D (C, E)	Polyubiquitin-C	polymer	76	8590.9	2	UniProt (P0CG48) Pfam (PF00240)	Homo sapiens (human)
4	E (E)	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	1	Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (40467049) PubChem (40469468) PubChem (44348067) PubChem (45358029) PubChem (46874558) PubChem (40459109) PubChem (46875232) PubChem (177678969) PubChem (6083) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (1549371) PubChem (92144436) PubChem (224) PubChem (12358354) PubChem (34768) PubChem (83862) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (122197642) PubChem (5316444) PubChem (5742864) PubChem (12163610) PubChem (12358355) PubChem (162290139) PubChem (162946266) PubChem (171699505)

Sequence modifications

A: 4577 - 4879 (UniProt: A0A0B4KG50)

PDB	External Database	Details
Gly 4575	-	expression tag
Pro 4576	-	expression tag

B: 184 - 1191 (UniProt: Q8T0L3)

PDB	External Database	Details
Gly 182	-	expression tag
Pro 183	-	expression tag

C, E: 1 - 76 (UniProt: P0CG48)

PDB	External Database	Details
Ala 76	Gly 76	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	164792.2
Non-Polymers*	Number of molecules	1
	Total formula weight	347.2
All*	Total formula weight	165139.4

*Water molecules are not included.