9QFO
Cryo-EM structure of the cofilactin filament pointed end
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (G, H, I, J) | Cofilin-1 | polymer | 166 | 18532.5 | 4 | UniProt (P23528) Pfam (PF00241) | Homo sapiens (human) | 18 kDa phosphoprotein,p18,Cofilin,non-muscle isoform |
| 2 | E, F, G, H, I... (A, B, C, D, E...) | Actin, cytoplasmic 1, N-terminally processed | polymer | 374 | 41632.4 | 6 | UniProt (P60709) Pfam (PF00022) | Homo sapiens (human) | |
| 3 | K, M, O, Q, S... (A, B, C, D, E...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 6 | Chemie (ADP) | |||
| 4 | L, N, P, R, T... (A, B, C, D, E...) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) |
Sequence modifications
A, B, C, D, E, F: 2 - 375 (UniProt: P60709)
| PDB | External Database | Details |
|---|---|---|
| Ala 272 | Cys 272 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 323924.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2709.0 | |
| All* | Total formula weight | 326633.7 |
