9QFJ
Cryo-EM structure of the cofilactin filament core at 2.3 Angstrom resolution.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (G, F, H, I, J) | Cofilin-1 | polymer | 166 | 18532.5 | 5 | UniProt (P23528) Pfam (PF00241) | Homo sapiens (human) | 18 kDa phosphoprotein,p18,Cofilin,non-muscle isoform |
| 2 | F, G, H, I, J (A, B, C, D, E) | Actin, cytoplasmic 1, N-terminally processed | polymer | 374 | 41632.4 | 5 | UniProt (P60709) Pfam (PF00022) | Homo sapiens (human) | |
| 3 | K, M, O, Q, S (A, B, C, D, E) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 5 | Chemie (ADP) | |||
| 4 | L, N, P, R, T (A, B, C, D, E) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 5 | AA, BA, CA, DA, U... (B, C, D, E, G...) | water | water | 18.0 | 857 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 2 - 375 (UniProt: P60709)
| PDB | External Database | Details |
|---|---|---|
| Ala 272 | Cys 272 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 300824.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2257.5 | |
| All* | Total formula weight | 303082.3 |
