9QFD
Cryo-EM structure of the fully cofilin-1-decorated actin filament (cofilactin)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Actin, cytoplasmic 1, N-terminally processed | polymer | 374 | 41632.4 | 7 | UniProt (P60709) Pfam (PF00022) | Homo sapiens (human) | |
| 2 | H, I, J, K, L... (H, I, J, K, L...) | Cofilin-1 | polymer | 166 | 18532.5 | 7 | UniProt (P23528) Pfam (PF00241) | Homo sapiens (human) | 18 kDa phosphoprotein,p18,Cofilin,non-muscle isoform |
| 3 | AA, O, Q, S, U... (G, A, B, C, D...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 7 | Chemie (ADP) | |||
| 4 | BA, P, R, T, V... (G, A, B, C, D...) | MAGNESIUM ION | non-polymer | 24.3 | 7 | Chemie (MG) |
Sequence modifications
A, B, C, D, E, F, G: 2 - 375 (UniProt: P60709)
| PDB | External Database | Details |
|---|---|---|
| Ala 272 | Cys 272 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 421154.7 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 3160.5 | |
| All* | Total formula weight | 424315.2 |
