9QF1
Structure of CHIP E3 ubiquitin ligase TPR domain in complex with compound 2
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | E3 ubiquitin-protein ligase CHIP | polymer | 136 | 15635.8 | 1 | UniProt (Q9UNE7) Pfam (PF12895) | Homo sapiens (human) | Antigen NY-CO-7,CLL-associated antigen KW-8,Carboxy terminus of Hsp70-interacting protein,RING-type E3 ubiquitin transferase CHIP,STIP1 homology and U box-containing protein 1 |
| 2 | B (A) | ~{N}-methyl-~{N}-[(1~{R})-1-pyridin-2-yl-3-pyrrolidin-1-yl-propyl]-5-[4,5,6,7-tetrakis(fluoranyl)-1~{H}-indol-3-yl]-1,3,4-oxadiazol-2-amine | non-polymer | 474.5 | 1 | Chemie (A1I5T) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence modifications
A: 23 - 154 (UniProt: Q9UNE7)
| PDB | External Database | Details |
|---|---|---|
| Gly 19 | - | expression tag |
| Ser 20 | - | expression tag |
| His 21 | - | expression tag |
| Met 22 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15635.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 570.5 | |
| All* | Total formula weight | 16206.3 |
