9QEC
Cryo-EM structure of the XPF-ERCC1-XPA complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA repair endonuclease XPF | polymer | 935 | 106894.5 | 1 | UniProt (Q92889) Pfam (PF02732) | Homo sapiens (human) | DNA excision repair protein ERCC-4,DNA repair protein complementing XP-F cells,Xeroderma pigmentosum group F-complementing protein |
| 2 | B (B) | DNA excision repair protein ERCC-1 | polymer | 297 | 32598.3 | 1 | UniProt (P07992) Pfam (PF03834) Pfam (PF00633) | Homo sapiens (human) | |
| 3 | C (C) | DNA repair protein complementing XP-A cells | polymer | 273 | 31422.1 | 1 | UniProt (P23025) Pfam (PF01286) Pfam (PF05181) | Homo sapiens (human) | Xeroderma pigmentosum group A-complementing protein |
Sequence modifications
A: 1 - 916 (UniProt: Q92889)
| PDB | External Database | Details |
|---|---|---|
| Met -18 | - | initiating methionine |
| Gly -17 | - | expression tag |
| Ser -16 | - | expression tag |
| Ser -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| Glu -8 | - | expression tag |
| Asn -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Tyr -5 | - | expression tag |
| Phe -4 | - | expression tag |
| Gln -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 170914.9 | |
| All* | Total formula weight | 170914.9 |
