9QDM
CRYO-EM STRUCTURE OF THE YEAST RESPIRATORY COMPLEX II WITH THE INHIBITOR BIXAFEN
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | polymer | 640 | 70404.5 | 1 | UniProt (Q00711) | Saccharomyces cerevisiae (brewer's yeast) | Flavoprotein subunit of complex II,FP |
| 2 | B (B) | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | polymer | 266 | 30347.4 | 1 | UniProt (P21801) | Saccharomyces cerevisiae (brewer's yeast) | Iron-sulfur subunit of complex II,Ip |
| 3 | C (C) | Succinate dehydrogenase [ubiquinone] cytochrome b subunit, mitochondrial | polymer | 198 | 22167.0 | 1 | UniProt (P33421) | Saccharomyces cerevisiae W303 | |
| 4 | D (D) | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | polymer | 196 | 22081.5 | 1 | UniProt (P37298) | Saccharomyces cerevisiae (brewer's yeast) | CybS,Succinate-ubiquinone reductase membrane anchor subunit |
| 5 | E (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 6 | F (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 7 | G (B) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 1 | Chemie (FES) | |||
| 8 | H (B) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
| 9 | I (B) | FE3-S4 CLUSTER | non-polymer | 295.8 | 1 | Chemie (F3S) | |||
| 10 | J (B) | bixafen | non-polymer | 414.2 | 1 | Chemie (A1I6X) | |||
| 11 | K (D) | 1,2-Distearoyl-sn-glycerophosphoethanolamine | non-polymer | 748.1 | 1 | Chemie (3PE) | |||
| 12 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
C: 1 - 198 (UniProt: P33421)
D: 1 - 181 (UniProt: P37298)
| PDB | External Database | Details |
|---|---|---|
| Pro 13 | Ser 13 | variant |
| Arg 74 | Lys 74 | variant |
| Phe 95 | Leu 95 | variant |
| PDB | External Database | Details |
|---|---|---|
| Gly 182 | - | expression tag |
| Ala 183 | - | expression tag |
| Arg 184 | - | expression tag |
| Gly 185 | - | expression tag |
| Ser 186 | - | expression tag |
| His 187 | - | expression tag |
| His 188 | - | expression tag |
| His 189 | - | expression tag |
| His 190 | - | expression tag |
| His 191 | - | expression tag |
| His 192 | - | expression tag |
| His 193 | - | expression tag |
| His 194 | - | expression tag |
| His 195 | - | expression tag |
| His 196 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 145000.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2810.2 | |
| All* | Total formula weight | 147810.5 |
