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9QCS

Ku80 mediated DNA-PK dimer bound to 153 bp H2AX nucleosome

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, L
(O, o)
DNA-dependent protein kinase catalytic subunitpolymer4128469673.22UniProt (P78527)Homo sapiens (human)DNA-PK catalytic subunit,DNA-PKcs,DNPK1,p460
2B, D, I, P
(D, H, d, h)
Histone H2B type 1-Jpolymer12613935.24UniProt (P06899)Homo sapiens (human)Histone H2B.1,Histone H2B.r,H2B/r
3C, E, H, O
(C, G, c, g)
Histone H2AXpolymer14315172.64UniProt (P16104)Homo sapiens (human)H2a/x,Histone H2A.X
4F, J, M, Q
(A, E, a, e)
Histone H3.1polymer13615437.24UniProt (P68431)Homo sapiens (human)Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l
5G, K, N, R
(B, F, b, f)
Histone H4polymer10311394.44UniProt (P62805)Homo sapiens (human)
6S, V
(i, I)
153 bp DNApolymer15347457.22Homo sapiens
7T, U
(j, J)
153 bp DNApolymer15346998.92Homo sapiens
8W, Y
(K, M)
X-ray repair cross-complementing protein 6polymer60969945.02UniProt (P12956)Homo sapiens (human)5'-deoxyribose-5-phosphate lyase Ku70,5'-dRP lyase Ku70,70 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 1,ATP-dependent DNA helicase II 70 kDa subunit,CTC box-binding factor 75 kDa subunit,CTCBF,DNA repair protein XRCC6,Lupus Ku autoantigen protein p70,Ku70,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 6
9X, Z
(L, N)
X-ray repair cross-complementing protein 5polymer73282812.42UniProt (P13010)Homo sapiens (human)86 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 2,ATP-dependent DNA helicase II 80 kDa subunit,CTC box-binding factor 85 kDa subunit,CTCBF,DNA repair protein XRCC5,Ku80,Ku86,Lupus Ku autoantigen protein p86,Nuclear factor IV,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains26
Total formula weight1657531.5
All*Total formula weight1657531.5
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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