9QBV
Crystal structure of WRN in complex with (R)-11 (GSK4766470)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN | polymer | 443 | 50480.9 | 1 | UniProt (Q14191) | Homo sapiens (human) | DNA helicase,RecQ-like type 3,RecQ protein-like 2,Werner syndrome protein |
| 2 | B (A) | 1-[(2~{R})-2-methyl-4-[2-[4-(trifluoromethyl)phenyl]ethanoyl]piperazin-1-yl]propan-1-one | non-polymer | 342.4 | 1 | Chemie (A1I5F) | |||
| 3 | C, D, E, F, G... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 4 | I (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | J (A) | water | water | 18.0 | 95 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 50480.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 780.2 | |
| All* | Total formula weight | 51261.1 |
