9QAQ
Human angiotensin-1 converting enzyme C-domain in complex with perindoprilat
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Angiotensin-converting enzyme, soluble form | polymer | 578 | 66778.5 | 1 | UniProt (P12821) Pfam (PF01401) | Homo sapiens (human) | |
| 2 | B (D) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D, E (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | F (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 6 | G, K, L, M, N... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 7 | H (A) | PERINDOPRILAT | non-polymer | 340.4 | 1 | Chemie (X94) | |||
| 8 | I, J (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 9 | P (A) | water | water | 18.0 | 296 | Chemie (HOH) |
Sequence modifications
A: 40 - 617 (UniProt: P12821)
| PDB | External Database | Details |
|---|---|---|
| Gly 64 | Glu 669 | engineered mutation |
| Gln 90 | Asn 695 | engineered mutation |
| Gln 155 | Asn 760 | engineered mutation |
| Gln 337 | Asn 942 | engineered mutation |
| Asp 345 | Thr 950 | engineered mutation |
| Gln 586 | Asn 1191 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 66778.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 732.7 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1360.6 | |
| All* | Total formula weight | 68871.9 |
