9QAQ
Human angiotensin-1 converting enzyme C-domain in complex with perindoprilat
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Angiotensin-converting enzyme, soluble form | polymer | 578 | 66778.5 | 1 | UniProt (P12821) Pfam (PF01401) | Homo sapiens (human) | |
| 2 | B (D) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D, E (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) PubChem (312) | |||
| 5 | F (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 6 | G, K, L, M, N... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 7 | H (A) | PERINDOPRILAT | non-polymer | 340.4 | 1 | Chemie (X94) PubChem (29986327) PubChem (44373617) PubChem (44373634) PubChem (72022) PubChem (45359064) PubChem (51426720) PubChem (51426722) PubChem (51426724) PubChem (58153613) PubChem (66971524) PubChem (69501780) PubChem (51426726) PubChem (73951950) PubChem (4687013) PubChem (101643817) PubChem (100888036) PubChem (139024130) PubChem (124825102) PubChem (124825103) PubChem (126968671) PubChem (129629063) PubChem (134692408) PubChem (143006400) PubChem (155075129) PubChem (175034913) PubChem (175034914) | |||
| 8 | I, J (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 9 | P (A) | water | water | 18.0 | 296 | Chemie (HOH) |
Sequence modifications
A: 40 - 617 (UniProt: P12821)
| PDB | External Database | Details |
|---|---|---|
| Gly 64 | Glu 669 | engineered mutation |
| Gln 90 | Asn 695 | engineered mutation |
| Gln 155 | Asn 760 | engineered mutation |
| Gln 337 | Asn 942 | engineered mutation |
| Asp 345 | Thr 950 | engineered mutation |
| Gln 586 | Asn 1191 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 66778.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 732.7 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1360.6 | |
| All* | Total formula weight | 68871.9 |
