9QAP
Human angiotensin-1 converting enzyme C-domain in complex with quinaprilat
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Angiotensin-converting enzyme, soluble form | polymer | 578 | 66764.6 | 1 | UniProt (P12821) Pfam (PF01401) | Homo sapiens (human) | |
| 2 | B (B) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1057.0 | 1 | In PDB GlyTouCan (G29616NS) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | quinaprilat | non-polymer | 410.5 | 1 | Chemie (A1I5A) | |||
| 5 | E (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 6 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | G, H (A) | BORIC ACID | non-polymer | 61.8 | 2 | Chemie (BO3) | |||
| 8 | I, J, K, M, N (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 9 | L (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 10 | O, P (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 11 | Q (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 12 | R (A) | water | water | 18.0 | 608 | Chemie (HOH) |
Sequence modifications
A: 40 - 609 (UniProt: P12821)
| PDB | External Database | Details |
|---|---|---|
| Gly 64 | Glu 669 | engineered mutation |
| Gln 90 | Asn 695 | engineered mutation |
| Gln 155 | Asn 760 | engineered mutation |
| Gln 333 | Asn 942 | engineered mutation |
| Gln 578 | Asn 1191 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 66764.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1057.0 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1271.1 | |
| All* | Total formula weight | 69092.6 |
