9Q9Q

TRIM21 PRYSPRY bound to compound 38

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, A)	E3 ubiquitin-protein ligase TRIM21	polymer	198	22518.2	2	UniProt (P19474) Pfam (PF13765) Pfam (PF00622)	Homo sapiens (human)	52 kDa Ro protein,52 kDa ribonucleoprotein autoantigen Ro/SS-A,RING finger protein 81,Ro(SS-A),Sjoegren syndrome type A antigen,SS-A,Tripartite motif-containing protein 21
2	C, D (B, A)	(2~{S},4~{S})-1-[(3~{S})-3-azanyl-3-(furan-2-yl)propanoyl]-4-cyclohexyl-~{N}-[(2~{S})-1-(methylamino)-1-oxidanylidene-3-pyridin-4-yl-propan-2-yl]pyrrolidine-2-carboxamide	non-polymer		495.6	2	Chemie (A1I4Y)

Sequence modifications

B, A: 4 - 192 (UniProt: P19474)

PDB	External Database	Details
Met -5	-	initiating methionine
Ala -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
Met 3	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45036.5
Non-Polymers*	Number of molecules	2
	Total formula weight	991.2
All*	Total formula weight	46027.7

*Water molecules are not included.