9Q8Z
Human chondroitin sulfate polymerase complex CHSY3-CHPF
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Chondroitin sulfate synthase 2 | polymer | 710 | 78847.5 | 1 | UniProt (Q8IZ52) Pfam (PF05679) | Homo sapiens (human) | Chondroitin glucuronyltransferase 2,Chondroitin-polymerizing factor,ChPF,Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II,N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II,N-acetylgalactosaminyltransferase 2 |
| 2 | B (B) | Chondroitin sulfate synthase 3 | polymer | 753 | 86456.5 | 1 | UniProt (Q70JA7) Pfam (PF05679) | Homo sapiens (human) | Carbohydrate synthase 2,Chondroitin glucuronyltransferase 3,Chondroitin synthase 2,ChSy-2,Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II,N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3,N-acetylgalactosaminyltransferase 3 |
| 3 | C, E, F (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 4 | D (B) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (57448939) PubChem (53486216) PubChem (60098857) PubChem (91746160) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (93088131) PubChem (93630083) PubChem (1158) PubChem (6031) PubChem (3084486) PubChem (6101632) PubChem (6604175) PubChem (11811538) PubChem (12049241) | |||
| 5 | G, H (B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) PubChem (27854) |
Sequence modifications
A: 81 - 775 (UniProt: Q8IZ52)
B: 156 - 882 (UniProt: Q70JA7)
| PDB | External Database | Details |
|---|---|---|
| Gly 74 | - | expression tag |
| Pro 75 | - | expression tag |
| Gly 76 | - | expression tag |
| Gly 77 | - | expression tag |
| Ser 78 | - | expression tag |
| Thr 79 | - | expression tag |
| Gly 80 | - | expression tag |
| Gly 776 | - | expression tag |
| Thr 777 | - | expression tag |
| Leu 778 | - | expression tag |
| Glu 779 | - | expression tag |
| Val 780 | - | expression tag |
| Leu 781 | - | expression tag |
| Phe 782 | - | expression tag |
| Gln 783 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 150 | - | expression tag |
| Pro 151 | - | expression tag |
| Gly 152 | - | expression tag |
| Gly 153 | - | expression tag |
| Ser 154 | - | expression tag |
| Thr 155 | - | expression tag |
| Gly 883 | - | expression tag |
| Thr 884 | - | expression tag |
| Gly 885 | - | expression tag |
| Ser 886 | - | expression tag |
| Gly 887 | - | expression tag |
| Leu 888 | - | expression tag |
| Asn 889 | - | expression tag |
| Asp 890 | - | expression tag |
| Ile 891 | - | expression tag |
| Phe 892 | - | expression tag |
| Glu 893 | - | expression tag |
| Ala 894 | - | expression tag |
| Gln 895 | - | expression tag |
| Lys 896 | - | expression tag |
| Ile 897 | - | expression tag |
| Glu 898 | - | expression tag |
| Trp 899 | - | expression tag |
| His 900 | - | expression tag |
| Glu 901 | - | expression tag |
| Gly 902 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 165304.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1177.7 | |
| All* | Total formula weight | 166481.7 |






