9Q8L
Crystal Structure of 21A08Ap1-Fab in Complex with Human PD-1 at 1.85 angstrom Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | Heavy chain of huIgG1-Fab | polymer | 218 | 23032.8 | 1 | Mus musculus | ||
| 2 | B (L) | Light chain of huIgG1-Fab | polymer | 216 | 22829.2 | 1 | Mus musculus | ||
| 3 | C (A) | Programmed cell death protein 1 | polymer | 147 | 16431.3 | 1 | UniProt (Q15116) Pfam (PF07686) | Homo sapiens (human) | Protein PD-1,hPD-1 |
| 4 | D, E (B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 5 | F, G, H, K (H, L) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 6 | I (H) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) PubChem (679) | |||
| 7 | J (L) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) PubChem (1061) | |||
| 8 | L (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 9 | M, N, O (H, L, A) | water | water | 18.0 | 343 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 62293.4 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1141.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 642.6 | |
| All* | Total formula weight | 64077.0 |
