9Q6J
Human prolyl endopeptidase (PREP) - complex with KT-2-126
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Prolyl endopeptidase | polymer | 711 | 80851.4 | 3 | UniProt (P48147) Pfam (PF02897) Pfam (PF00326) | Homo sapiens (human) | PE,Post-proline cleaving enzyme |
| 2 | D, EA, F, V (A, C, B) | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 4 | Chemie (B3P) | |||
| 3 | CA, E, T (C, A, B) | 4-chloro-N-[3-oxo-3-(pyrrolidin-1-yl)propyl]-3-phenyl-1-(2-phenylethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide | non-polymer | 502.0 | 3 | Chemie (A1CQ0) | |||
| 4 | DA, G, H, HA, IA... (C, A, B) | GLYCEROL | non-polymer | 92.1 | 16 | Chemie (GOL) | |||
| 5 | I, S (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 6 | AA, BA, FA, GA, K... (B, C, A) | THIOCYANATE ION | non-polymer | 58.1 | 11 | Chemie (SCN) | |||
| 7 | NA, OA, PA (A, B, C) | water | water | 18.0 | 1853 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 710 (UniProt: P48147)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 242554.1 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 4960.0 | |
| All* | Total formula weight | 247514.1 |
