9Q6I
Human prolyl endopeptidase (PREP) - complex with JP-6-1-7
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Prolyl endopeptidase | polymer | 711 | 80851.4 | 3 | UniProt (P48147) | Homo sapiens (human) | PE,Post-proline cleaving enzyme |
| 2 | D, Q, W (A, B, C) | 3-methyl-N-[3-oxo-3-(pyrrolidin-1-yl)propyl]-1-[(pyridin-2-yl)methyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide | non-polymer | 426.9 | 3 | Chemie (A1CQX) | |||
| 3 | E, F, J, K, O... (A, B, C) | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) PubChem (753) | |||
| 4 | AA, BA, CA, G, H... (C, A, B) | THIOCYANATE ION | non-polymer | 58.1 | 13 | Chemie (SCN) PubChem (9322) | |||
| 5 | X (C) | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 1 | Chemie (B3P) PubChem (125132) | |||
| 6 | DA, EA, FA (A, B, C) | water | water | 18.0 | 1319 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 710 (UniProt: P48147)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 242554.1 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 3146.9 | |
| All* | Total formula weight | 245701.0 |
