9Q65
Human prolyl endopeptidase (PREP) - complex with KT-2-75
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (B, D, F) | Prolyl endopeptidase | polymer | 711 | 80851.4 | 3 | UniProt (P48147) Pfam (PF02897) Pfam (PF00326) | Homo sapiens (human) | PE,Post-proline cleaving enzyme |
| 2 | D, O, U (B, D, F) | 4-chloro-1,3-dimethyl-N-[3-oxo-3-(pyrrolidin-1-yl)propyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide | non-polymer | 349.8 | 3 | Chemie (A1CQU) | |||
| 3 | E (B) | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 1 | Chemie (B3P) | |||
| 4 | F, G, H, L, M... (B, D) | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 5 | I, J, K, N, S... (B, D, F) | THIOCYANATE ION | non-polymer | 58.1 | 6 | Chemie (SCN) | |||
| 6 | V (F) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 7 | W, X, Y (B, D, F) | water | water | 18.0 | 416 | Chemie (HOH) |
Sequence modifications
B, D, F: 1 - 710 (UniProt: P48147)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 242554.1 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 2523.1 | |
| All* | Total formula weight | 245077.2 |
