9Q62
Human prolyl endopeptidase (PREP) - complex with KT-2-108
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Prolyl endopeptidase | polymer | 711 | 80851.4 | 3 | UniProt (P48147) Pfam (PF02897) Pfam (PF00326) | Homo sapiens (human) | PE,Post-proline cleaving enzyme |
| 2 | D, FA, T (A, C, B) | POTASSIUM ION | non-polymer | 39.1 | 3 | Chemie (K) | |||
| 3 | E, F, GA, U (A, C, B) | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 4 | Chemie (B3P) | |||
| 4 | G, HA, V (A, C, B) | 4-chloro-3-methyl-N-[3-oxo-3-(pyrrolidin-1-yl)propyl]-1-(2-phenylethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide | non-polymer | 439.9 | 3 | Chemie (A1CQQ) | |||
| 5 | AA, BA, CA, DA, H... (B, A, C) | THIOCYANATE ION | non-polymer | 58.1 | 15 | Chemie (SCN) | |||
| 6 | EA, IA, K, KA, L... (B, C, A) | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) | |||
| 7 | LA, MA, NA (A, B, C) | water | water | 18.0 | 1389 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 710 (UniProt: P48147)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 242554.1 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 4266.5 | |
| All* | Total formula weight | 246820.6 |
