9Q5D
Crystal Structure of WT HIV-1 Protease (NL4-3) with Inhibitor J02-37
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Protease | polymer | 99 | 10831.8 | 2 | UniProt (P12497) | Human immunodeficiency virus 1 | PR,Retropepsin |
| 2 | C (B) | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-1-(3,5-difluorophenyl)-3-hydroxy-4-({4-[(1R)-1-hydroxyethyl]benzene-1-sulfonyl}[(2S)-2-methylbutyl]amino)butan-2-yl]carbamate | non-polymer | 626.7 | 1 | Chemie (A1COE) | |||
| 3 | D (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) PubChem (8117) | |||
| 4 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 5 | F, G (B, A) | water | water | 18.0 | 169 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 99 (UniProt: P12497)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 495 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21663.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 824.9 | |
| All* | Total formula weight | 22488.6 |
