9PZS
Native GluN1/GluN2A/GluN2B in complex with 5F11 and 3D2 Fabs (class 1), glycine and glutamate bound state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (D) | Glutamate receptor ionotropic, NMDA 2B | polymer | 1482 | 166162.1 | 1 | UniProt (Q01097) Pfam (PF00060) Pfam (PF10565) Pfam (PF01094) Pfam (PF10613) | Mus musculus (house mouse) | GluN2B,Glutamate [NMDA] receptor subunit epsilon-2,N-methyl D-aspartate receptor subtype 2B,NMDAR2B,NR2B |
| 2 | B, F (A, C) | Glutamate receptor ionotropic, NMDA 1 | polymer | 938 | 105617.8 | 2 | UniProt (P35438) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Mus musculus (house mouse) | GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1 |
| 3 | C, I (F, H) | Heavy chain of GluN1-specific monoclonal Fab fragment, termed 5F11 | polymer | 277 | 29432.5 | 2 | Mus musculus | ||
| 4 | D, J (G, I) | Light chain of GluN1-specific monoclonal Fab fragment, termed 5F11 | polymer | 244 | 26910.0 | 2 | Mus musculus | ||
| 5 | E (B) | Glutamate receptor ionotropic, NMDA 2A | polymer | 1464 | 165619.9 | 1 | UniProt (P35436) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) Pfam (PF10565) | Mus musculus (house mouse) | GluN2A,Glutamate [NMDA] receptor subunit epsilon-1,N-methyl D-aspartate receptor subtype 2A,NMDAR2A,NR2A |
| 6 | G (J) | Heavy chain of GluN2A-specific monoclonal Fab fragment, termed 3D2 | polymer | 141 | 15448.5 | 1 | Mus musculus | ||
| 7 | H (K) | Light chain of GluN2A-specific monoclonal Fab fragment, termed 3D2 | polymer | 131 | 13989.8 | 1 | Mus musculus | ||
| 8 | K, L, N, O, P (E, L, N, O, P) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 5 | In PDB GlyTouCan (G42666HT) | |||
| 9 | M (M) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 10 | Q, R, S (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 685140.9 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 2708.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 688513.1 |
