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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

9PZC

HCMV trimer in complex with G1L (II), G1L (A), B5L, C4K, B1K, A7K, A12K, and C5K Fabs

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)		Envelope glycoprotein Hpolymer74384538.61UniProt (Q69155)Human betaherpesvirus 5
2B
(B)		Envelope glycoprotein Lpolymer26829877.31UniProt (Q8JP80)Human betaherpesvirus 5gL
3C
(C)		Immunoglobulin lambda variable 1-51polymer11011542.81UniProt (P01701)Homo sapiens (human)Ig lambda chain V-I region BL2,Ig lambda chain V-I region EPS,Ig lambda chain V-I region NEW,Ig lambda chain V-I region NIG-64
4D
(D)		G1L Fab heavy chainpolymer12513754.71Homo sapiens
5E
(E)		Immunoglobulin heavy variable 1-46polymer11913243.91UniProt (P01743)Homo sapiens (human)Ig heavy chain V-I region DOT,Ig heavy chain V-I region HG3,Ig heavy chain V-I region Mot
6F
(F)		Immunoglobulin kappa variable 3-20polymer10811560.81UniProt (P01619)Homo sapiens (human)Ig kappa chain V-III region B6,Ig kappa chain V-III region GOL,Ig kappa chain V-III region HAH,Ig kappa chain V-III region HIC,Ig kappa chain V-III region IARC/BL41,Ig kappa chain V-III region NG9,Ig kappa chain V-III region SIE,Ig kappa chain V-III region Ti,Ig kappa chain V-III region WOL
7G
(G)		A12K Fab heavy chainpolymer11612971.71Homo sapiens
8H
(H)		Immunoglobulin heavy variable 4-34polymer12313668.21UniProt (P06331)Homo sapiens (human)Ig heavy chain V-II region ARH-77
9I
(I)		A12K Fab light chainpolymer10811702.11Homo sapiens
10J
(J)		Immunoglobulin kappa variable 1-39polymer10711679.01UniProt (P01597)Homo sapiens (human)Ig kappa chain V-I region DEE,Ig kappa chain V-I region Hau,Ig kappa chain V-I region Mev,Ig kappa chain V-I region OU,Ig kappa chain V-I region Walker
11K
(K)		Immunoglobulin heavy variable 4-39polymer12113333.81UniProt (P01824)Homo sapiens (human)Ig heavy chain V-II region WAH
12L
(L)		B5L Fab light chainpolymer11011503.51Homo sapiens
13M
(M)		C5K Fab light chainpolymer10611824.21Homo sapiens
14N
(N)		Immunoglobulin heavy variable 1-46polymer12313339.01UniProt (P01743)Homo sapiens (human)Ig heavy chain V-I region DOT,Ig heavy chain V-I region HG3,Ig heavy chain V-I region Mot
15O
(O)		C4K Fab heavy chainpolymer11913167.81Homo sapiens
16P
(P)		C4K Fab light chainpolymer10811697.01Homo sapiens
17Q, R, S
(A, B)		2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.23Chemie (NAG)
PubChem (24139)
Sequence modifications
A: 0 - 742 (UniProt: Q69155)
PDBExternal DatabaseDetails
Thr 12Ala 13conflict
B: 31 - 278 (UniProt: Q8JP80)
PDBExternal DatabaseDetails
Met 11-expression tag
Ser 12-expression tag
Val 13-expression tag
Pro 14-expression tag
Thr 15-expression tag
Gln 16-expression tag
Val 17-expression tag
Leu 18-expression tag
Gly 19-expression tag
Leu 20-expression tag
Leu 21-expression tag
Leu 22-expression tag
Leu 23-expression tag
Trp 24-expression tag
Leu 25-expression tag
Thr 26-expression tag
Asp 27-expression tag
Ala 28-expression tag
Arg 29-expression tag
Cys 30-expression tag
Glu 41Lys 41conflict
Arg 77Gly 77conflict
C: 1 - 95 (UniProt: P01701)
PDBExternal DatabaseDetails
Leu 11Val 29conflict
Arg 18Lys 36conflict
Thr 24Ser 42conflict
Thr 27Ser 45conflict
Val 29Gly 49conflict
His 38Gln 58conflict
Val 52Asn 72conflict
Ser 59Pro 79conflict
Thr 70Ser 90conflict
Thr 74Gly 94conflict
Ser 84Ala 104conflict
Leu 95-expression tag
Gly 96-expression tag
Val 97-expression tag
Phe 98-expression tag
Gly 99-expression tag
Gly 100-expression tag
Gly 101-expression tag
Thr 102-expression tag
Lys 103-expression tag
Val 104-expression tag
Thr 105-expression tag
Val 106-expression tag
Leu 106-expression tag
E: 1 - 94 (UniProt: P01743)
PDBExternal DatabaseDetails
Met 18Val 37conflict
Asn 31Ser 50conflict
Leu 34Met 53conflict
Leu 50Ile 69conflict
Asp 52Asn 71conflict
Asn 56Ser 76conflict
Asn 58Ser 78conflict
Arg 73Thr 93conflict
Pro 84Ser 107conflict
Thr 88Ala 111conflict
Gly 95-expression tag
Gly 96-expression tag
Tyr 97-expression tag
Asn 98-expression tag
Ser 99-expression tag
Arg 100-expression tag
Leu 100-expression tag
Arg 100-expression tag
Leu 100-expression tag
Asp 101-expression tag
Ser 102-expression tag
Trp 103-expression tag
Gly 104-expression tag
Gln 105-expression tag
Gly 106-expression tag
Thr 107-expression tag
Leu 108-expression tag
Val 109-expression tag
Thr 110-expression tag
Val 111-expression tag
Ser 112-expression tag
F: 1 - 95 (UniProt: P01619)
PDBExternal DatabaseDetails
Ser 40Pro 61conflict
Ala 66Gly 87conflict
Leu 85Val 106conflict
Leu 96-expression tag
Thr 97-expression tag
Phe 98-expression tag
Gly 99-expression tag
Gly 100-expression tag
Gly 101-expression tag
Thr 102-expression tag
Lys 103-expression tag
Val 104-expression tag
Glu 105-expression tag
Ile 106-expression tag
Lys 107-expression tag
H: 1 - 94 (UniProt: P06331)
PDBExternal DatabaseDetails
Trp 15Ser 41conflict
Ile 29Phe 55conflict
Asn 30Ser 56conflict
Glu 31Gly 57conflict
Gly 43Lys 69conflict
Ile 67Val 93conflict
Thr 69Ile 95conflict
Arg 81Lys 107conflict
Val 84Ala 113conflict
Gly 95-expression tag
His 96-expression tag
Arg 97-expression tag
Lys 98-expression tag
Gly 99-expression tag
Ala 100-expression tag
Arg 100-expression tag
Ile 100-expression tag
Ser 100-expression tag
Gly 100-expression tag
Arg 100-expression tag
Asn 100-expression tag
Trp 100-expression tag
Phe 100-expression tag
Asp 101-expression tag
Pro 102-expression tag
Trp 103-expression tag
Gly 104-expression tag
Gln 105-expression tag
Gly 106-expression tag
Ser 107-expression tag
Leu 108-expression tag
Val 109-expression tag
Thr 110-expression tag
Val 111-expression tag
Ser 112-expression tag
J: 1 - 95 (UniProt: P01597)
PDBExternal DatabaseDetails
Thr 31Ser 53conflict
Arg 37Gln 59conflict
Ser 45Lys 67conflict
Ile 51Ala 73conflict
Thr 56Ser 78conflict
Asn 76Ser 98conflict
Asn 77Ser 99conflict
Phe 92Tyr 114conflict
Arg 96-expression tag
Thr 97-expression tag
Phe 98-expression tag
Gly 99-expression tag
Gln 100-expression tag
Gly 101-expression tag
Thr 102-expression tag
Lys 103-expression tag
Val 104-expression tag
Glu 105-expression tag
Ile 106-expression tag
Lys 107-expression tag
K: 1 - 94 (UniProt: P01824)
PDBExternal DatabaseDetails
Val 2Leu 28conflict
Ala 27Gly 53conflict
Gly 33Ser 59conflict
Ser 40Pro 68conflict
Thr 50Ser 78conflict
Asn 75Lys 103conflict
Met 80Leu 108conflict
Val 93Ala 124conflict
Arg 95-expression tag
Val 96-expression tag
Thr 97-expression tag
Tyr 98-expression tag
Thr 99-expression tag
Lys 100-expression tag
Thr 100-expression tag
Trp 100-expression tag
Ala 100-expression tag
Phe 100-expression tag
Asp 101-expression tag
Tyr 102-expression tag
Trp 103-expression tag
Gly 104-expression tag
Gln 105-expression tag
Gly 106-expression tag
Thr 107-expression tag
Leu 108-expression tag
Val 109-expression tag
Thr 110-expression tag
Val 111-expression tag
Ser 112-expression tag
N: 1 - 94 (UniProt: P01743)
PDBExternal DatabaseDetails
Asp 27Tyr 46conflict
Leu 29Phe 48conflict
Arg 30Thr 49conflict
Arg 31Ser 50conflict
Ile 34Met 53conflict
Thr 58Ser 78conflict
Ser 68Thr 88conflict
Arg 82Ser 103conflict
Asp 85Glu 108conflict
Gly 95-expression tag
Gly 96-expression tag
Pro 97-expression tag
Thr 98-expression tag
Val 99-expression tag
Val 100-expression tag
Val 100-expression tag
Val 100-expression tag
Ala 100-expression tag
Ala 100-expression tag
Thr 100-expression tag
Pro 100-expression tag
Phe 100-expression tag
Asp 101-expression tag
Asp 102-expression tag
Trp 103-expression tag
Gly 104-expression tag
Gln 105-expression tag
Gly 106-expression tag
Thr 107-expression tag
Leu 108-expression tag
Val 109-expression tag
Thr 110-expression tag
Val 111-expression tag
Ser 112-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains16
Total formula weight289404.4
Non-Polymers*Number of molecules3
Total formula weight663.6
All*Total formula weight290068.0
*Water molecules are not included.

255900

PDB entries from 2026-07-01

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