9PZ1
Crystal structure of WT HIV-1 protease (NL4-3) with inhibitor LR4-43
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protease | polymer | 99 | 10831.8 | 2 | UniProt (P12497) | Human immunodeficiency virus 1 | PR,Retropepsin |
| 2 | C (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 3 | D (A) | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-1-(3,5-difluorophenyl)-4-[(2-ethylbutyl){4-[(1S)-1-hydroxyethyl]benzene-1-sulfonyl}amino]-3-hydroxybutan-2-yl}carbamate | non-polymer | 640.7 | 1 | Chemie (A1CM6) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 131 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P12497)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 495 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21663.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 718.9 | |
| All* | Total formula weight | 22382.5 |
