9PXB
Hamster Scap/Insig-2 complex with cholesterol and bound Fab4G10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sterol regulatory element-binding protein cleavage-activating protein | polymer | 797 | 89014.7 | 1 | UniProt (P97260) | Cricetulus griseus (Chinese hamster) | SCAP,SREBP cleavage-activating protein |
| 2 | B (C) | Insulin-induced gene protein | polymer | 225 | 24929.9 | 1 | UniProt (Q8CFA5) | Cricetulus griseus (Chinese hamster) | |
| 3 | C (H) | Fab4G10 heavy chain | polymer | 252 | 27016.9 | 1 | Mus musculus | ||
| 4 | D (L) | Fab4G10 light chain | polymer | 229 | 25545.2 | 1 | Mus musculus | ||
| 5 | E (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 6 | F, G, H (C) | CHOLESTEROL | non-polymer | 386.7 | 3 | Chemie (CLR) |
Sequence modifications
A: 2 - 752 (UniProt: P97260)
| PDB | External Database | Details |
|---|---|---|
| Met -44 | - | expression tag |
| Asp -43 | - | expression tag |
| Tyr -42 | - | expression tag |
| Lys -41 | - | expression tag |
| Asp -40 | - | expression tag |
| Asp -39 | - | expression tag |
| Asp -38 | - | expression tag |
| Asp -37 | - | expression tag |
| Lys -36 | - | expression tag |
| Gly -35 | - | expression tag |
| Ser -34 | - | expression tag |
| Asp -33 | - | expression tag |
| Tyr -32 | - | expression tag |
| Lys -31 | - | expression tag |
| Asp -30 | - | expression tag |
| Asp -29 | - | expression tag |
| Asp -28 | - | expression tag |
| Asp -27 | - | expression tag |
| Lys -26 | - | expression tag |
| Gly -25 | - | expression tag |
| Ser -24 | - | expression tag |
| Asp -23 | - | expression tag |
| Tyr -22 | - | expression tag |
| Lys -21 | - | expression tag |
| Asp -20 | - | expression tag |
| Asp -19 | - | expression tag |
| Asp -18 | - | expression tag |
| Asp -17 | - | expression tag |
| Lys -16 | - | expression tag |
| Glu -15 | - | expression tag |
| Asn -14 | - | expression tag |
| Leu -13 | - | expression tag |
| Tyr -12 | - | expression tag |
| Phe -11 | - | expression tag |
| Gln -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Thr -8 | - | expression tag |
| Gly -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| Ala 133 | Val 133 | engineered mutation |
| Val 140 | Thr 140 | engineered mutation |
| Asp 244 | His 244 | engineered mutation |
| Ser 245 | Ala 245 | engineered mutation |
| Arg 246 | Lys 246 | engineered mutation |
| Ser 253 | Ala 253 | engineered mutation |
| Lys 256 | Met 256 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 166506.7 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1160.0 | |
| All* | Total formula weight | 168091.0 |
