9PWI

EGFR kinase bound to ZNL-1

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Epidermal growth factor receptor	polymer	331	37636.4	1	UniProt (P00533) Pfam (PF07714)	Homo sapiens (human)	Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1
2	B (A)	N-[2-({1-methyl-7-[4-(4-methylpiperazin-1-yl)anilino]-2-oxo-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2H)-yl}methyl)phenyl]prop-2-enamide	non-polymer		512.6	1	Chemie (A1CMF)
3	C (A)	water	water		18.0	3	Chemie (HOH)

Sequence modifications

A: 695 - 1022 (UniProt: P00533)

PDB	External Database	Details
Gly 692	-	expression tag
Ser 693	-	expression tag
Thr 694	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	37636.4
Non-Polymers*	Number of molecules	1
	Total formula weight	512.6
All*	Total formula weight	38149.0

*Water molecules are not included.