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9PWE

Menthol-bound mouse TRPM8 in complex with AITC and PIP2 in a closed (C1M') state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Transient receptor potential cation channel subfamily M member 8polymer1104127855.54UniProt (Q8R4D5)Mus musculus (house mouse)Long transient receptor potential channel 6,LTrpC-6,LTrpC6,Transient receptor potential p8,Trp-p8
2E, K, Q, W
(A, B, C, D)
[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoatenon-polymer746.64Chemie (PIO)
3F, G, H, L, M...
(A, B, C, D)
TETRADECANEnon-polymer198.412Chemie (C14)
PubChem (12389)
4AA, I, O, U
(D, A, B, C)
3-isothiocyanatoprop-1-enenon-polymer99.24Chemie (UL9)
PubChem (5971)
5BA, J, P, V
(D, A, B, C)
(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-olnon-polymer156.34Chemie (XUQ)
PubChem (16666)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight511422.0
Non-Polymers*Number of molecules24
Total formula weight6388.6
All*Total formula weight517810.6
*Water molecules are not included.

260626

PDB entries from 2026-10-07

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