9PWC
Composite structure of AP-2 bound to the dileucine motif and WxxPhi motif of CCDC32
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | AP-2 complex subunit alpha-2 | polymer | 630 | 70573.3 | 1 | UniProt (P17427) | Mus musculus (house mouse) | 100 kDa coated vesicle protein C,Adaptor protein complex AP-2 subunit alpha-2,Adaptor-related protein complex 2 subunit alpha-2,Alpha-adaptin C,Alpha2-adaptin,Clathrin assembly protein complex 2 alpha-C large chain,Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit |
| 2 | B (B) | AP-2 complex subunit beta | polymer | 591 | 66953.2 | 1 | UniProt (Q9DBG3) | Mus musculus (house mouse) | AP105B,Adaptor protein complex AP-2 subunit beta,Adaptor-related protein complex 2 subunit beta,Beta-2-adaptin,Beta-adaptin,Clathrin assembly protein complex 2 beta large chain,Plasma membrane adaptor HA2/AP2 adaptin beta subunit |
| 3 | C (C) | Coiled-coil domain-containing protein 32 | polymer | 179 | 19953.2 | 1 | UniProt (Q8BS39) | Mus musculus (house mouse) | |
| 4 | D (M) | AP-2 complex subunit mu | polymer | 435 | 49726.6 | 1 | UniProt (P84091) | Mus musculus (house mouse) | AP-2 mu chain,Adaptor protein complex AP-2 subunit mu,Adaptor-related protein complex 2 subunit mu,Clathrin assembly protein complex 2 mu medium chain,Clathrin coat assembly protein AP50,Clathrin coat-associated protein AP50,Mu2-adaptin,Plasma membrane adaptor AP-2 50 kDa protein |
| 5 | E (S) | AP-2 complex subunit sigma | polymer | 142 | 17038.7 | 1 | UniProt (P62743) | Mus musculus (house mouse) | Adaptor protein complex AP-2 subunit sigma,Adaptor-related protein complex 2 subunit sigma,Clathrin assembly protein 2 sigma small chain,Clathrin coat assembly protein AP17,Clathrin coat-associated protein AP17,Plasma membrane adaptor AP-2 17 kDa protein,Sigma-adaptin 3b,Sigma2-adaptin |
Sequence modifications
A: 1 - 621 (UniProt: P17427)
| PDB | External Database | Details |
|---|---|---|
| Glu 272 | - | insertion |
| Gly 622 | - | expression tag |
| Ser 623 | - | expression tag |
| Gly 624 | - | expression tag |
| Leu 625 | - | expression tag |
| Glu 626 | - | expression tag |
| Val 627 | - | expression tag |
| Leu 628 | - | expression tag |
| Phe 629 | - | expression tag |
| Gln 630 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 224245.0 | |
| All* | Total formula weight | 224245.0 |






