9PW7
Myeloid cell leukemia-1 (Mcl-1) complexed with compound 13
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Maltodextrin-binding protein,Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 517 | 57414.1 | 1 | UniProt (A0A4P1LXE0) UniProt (Q07820) Pfam (PF01547) Pfam (PF00452) | Homo sapiens (human) | Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
| 2 | B (B) | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB GlyTouCan (G07411ON) | |||
| 3 | C (A) | (2S,4R,5S,12P,23R)-11-chloro-7-[3-(4-chloro-3,5-dimethylphenoxy)propyl]-27,28-dimethoxy-4,15-dimethyl-32-oxo-19-oxa-2,5,15,16,23-pentaazaheptacyclo[21.6.1.1~2,6~.1~5,8~.0~12,31~.0~13,17~.0~26,30~]dotriaconta-1(30),6,8(31),9,11,13,16,24,26,28-decaene-24-carboxylic acid (non-preferred name) | non-polymer | 800.7 | 1 | Chemie (A1CL6) | |||
| 4 | D (A) | water | water | 18.0 | 331 | Chemie (HOH) |
Sequence modifications
A: -196 - 170 (UniProt: A0A4P1LXE0)
A: 173 - 320 (UniProt: Q07820)
| PDB | External Database | Details |
|---|---|---|
| Gly 171 | - | linker |
| Ser 172 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 57414.1 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 800.7 | |
| All* | Total formula weight | 58557.1 |
