9PVP

Cryo-EM structure of receptor tyrosine kinase ROS1 extracellular domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Proto-oncogene tyrosine-protein kinase ROS	polymer	1854	207759.4	1	UniProt (Q78DX7)	Mus musculus (house mouse)	Proto-oncogene c-Ros,Proto-oncogene c-Ros-1,Receptor tyrosine kinase c-ros oncogene 1,c-Ros receptor tyrosine kinase
2	B, C, D, E, F... (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	11	Chemie (NAG)

Sequence modifications

A: 28 - 1847 (UniProt: Q78DX7)

PDB	External Database	Details
Gly 1848	-	expression tag
Gly 1849	-	expression tag
Gly 1850	-	expression tag
Ser 1851	-	expression tag
Ser 1852	-	expression tag
Ala 1853	-	expression tag
Trp 1854	-	expression tag
Ser 1855	-	expression tag
His 1856	-	expression tag
Pro 1857	-	expression tag
Gln 1858	-	expression tag
Phe 1859	-	expression tag
Glu 1860	-	expression tag
Lys 1861	-	expression tag
Gly 1862	-	expression tag
Gly 1863	-	expression tag
Gly 1864	-	expression tag
Ser 1865	-	expression tag
Gly 1866	-	expression tag
Gly 1867	-	expression tag
Gly 1868	-	expression tag
Ser 1869	-	expression tag
Gly 1870	-	expression tag
Gly 1871	-	expression tag
Ser 1872	-	expression tag
Ala 1873	-	expression tag
Trp 1874	-	expression tag
Ser 1875	-	expression tag
His 1876	-	expression tag
Pro 1877	-	expression tag
Gln 1878	-	expression tag
Phe 1879	-	expression tag
Glu 1880	-	expression tag
Lys 1881	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	207759.4
Non-Polymers*	Number of molecules	11
	Total formula weight	2433.3
All*	Total formula weight	210192.7

*Water molecules are not included.