9PUP

Human respirovirus 3 hemagglutinin-neuraminidase dimer in complex with VHH A2R3-59

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (I, H)	VHH A2R3-59	polymer	132	14153.4	2		Vicugna pacos
2	B, D (B, A)	Hemagglutinin-neuraminidase	polymer	502	55954.8	2	UniProt (P12561)	Human respirovirus 3
3	E, F (C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
4	G, H, I, J (B, A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG) PubChem (24139)

Sequence modifications

B, A: 141 - 572 (UniProt: P12561)

PDB	External Database	Details
Met 71	-	initiating methionine
Pro 72	-	expression tag
Met 73	-	expression tag
Gly 74	-	expression tag
Ser 75	-	expression tag
Leu 76	-	expression tag
Gln 77	-	expression tag
Pro 78	-	expression tag
Leu 79	-	expression tag
Ala 80	-	expression tag
Thr 81	-	expression tag
Leu 82	-	expression tag
Tyr 83	-	expression tag
Leu 84	-	expression tag
Leu 85	-	expression tag
Gly 86	-	expression tag
Met 87	-	expression tag
Leu 88	-	expression tag
Val 89	-	expression tag
Ala 90	-	expression tag
Ser 91	-	expression tag
Val 92	-	expression tag
Leu 93	-	expression tag
Ser 94	-	expression tag
Ala 95	-	expression tag
Trp 96	-	expression tag
Ser 97	-	expression tag
His 98	-	expression tag
Pro 99	-	expression tag
Gln 100	-	expression tag
Phe 101	-	expression tag
Glu 102	-	expression tag
Lys 103	-	expression tag
Gly 104	-	expression tag
Ser 105	-	expression tag
Met 106	-	expression tag
Lys 107	-	expression tag
Gln 108	-	expression tag
Leu 109	-	expression tag
Glu 110	-	expression tag
Asp 111	-	expression tag
Lys 112	-	expression tag
Ile 113	-	expression tag
Glu 114	-	expression tag
Glu 115	-	expression tag
Leu 116	-	expression tag
Leu 117	-	expression tag
Ser 118	-	expression tag
Lys 119	-	expression tag
Ile 120	-	expression tag
Tyr 121	-	expression tag
His 122	-	expression tag
Leu 123	-	expression tag
Glu 124	-	expression tag
Asn 125	-	expression tag
Glu 126	-	expression tag
Ile 127	-	expression tag
Ala 128	-	expression tag
Arg 129	-	expression tag
Leu 130	-	expression tag
Lys 131	-	expression tag
Lys 132	-	expression tag
Leu 133	-	expression tag
Ile 134	-	expression tag
Gly 135	-	expression tag
Glu 136	-	expression tag
Gly 137	-	expression tag
Ala 138	-	expression tag
Gly 139	-	expression tag
Ser 140	-	expression tag
Ser 174	Leu 174	conflict
Tyr 295	His 295	conflict
Val 391	Ile 391	conflict
Ser 501	Thr 501	conflict
Asn 556	Asp 556	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	140216.3
Branched	Number of molecules	2
	Total formula weight	848.8
Non-Polymers*	Number of molecules	4
	Total formula weight	884.8
All*	Total formula weight	141950.0

*Water molecules are not included.