9PUH
SARS-CoV-2 Papain-like Protease (PLpro) in complex with Fragment 11
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (D, A, B) | Papain-like protease nsp3 | polymer | 318 | 35923.7 | 3 | UniProt (P0DTD1) Pfam (PF08715) | Severe acute respiratory syndrome coronavirus 2 | Non-structural protein 3,nsp3,PL2-PRO,Papain-like proteinase,PL-PRO |
| 2 | D, G (D, B) | 1'-methylspiro[[1]benzopyran-2,4'-piperidin]-4(3H)-one | non-polymer | 231.3 | 2 | Chemie (A1CLE) PubChem (1233903) | |||
| 3 | E, F, H (D, A, B) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) PubChem (32051) | |||
| 4 | I, J, K (D, A, B) | water | water | 18.0 | 291 | Chemie (HOH) |
Sequence modifications
D, A, B: 1 - 314 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
| Ser 111 | Cys 1674 | engineered mutation |
| Ser 270 | Cys 1833 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 107771.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 658.8 | |
| All* | Total formula weight | 108429.8 |
