9PRT
Human 19S proteasome bound to TXNL1 PITH domain but with low density for RPT1, RPT2, and RPN1
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | RPT6 | polymer | 406 | 45694.0 | 1 | UniProt (P62195) | Homo sapiens (human) | 26S proteasome AAA-ATPase subunit RPT6,Proteasome 26S subunit ATPase 5,Proteasome subunit p45,Thyroid hormone receptor-interacting protein 1,TRIP1,p45/SUG |
| 2 | B (D) | RPT3 | polymer | 418 | 47426.1 | 1 | UniProt (P43686) | Homo sapiens (human) | 26S proteasome AAA-ATPase subunit RPT3,MB67-interacting protein,MIP224,Proteasome 26S subunit ATPase 4,Tat-binding protein 7,TBP-7 |
| 3 | C (E) | RPT4 | polymer | 389 | 44241.0 | 1 | UniProt (P62333) | Homo sapiens (human) | 26S proteasome AAA-ATPase subunit RPT4,Proteasome 26S subunit ATPase 6,Proteasome subunit p42 |
| 4 | D (F) | RPT5 | polymer | 439 | 49266.5 | 1 | UniProt (P17980) | Homo sapiens (human) | 26S proteasome AAA-ATPase subunit RPT5,Proteasome 26S subunit ATPase 3,Proteasome subunit P50,Tat-binding protein 1,TBP-1 |
| 5 | E (U) | RPN2 | polymer | 953 | 105958.2 | 1 | UniProt (Q99460) | Homo sapiens (human) | 26S proteasome regulatory subunit RPN2,26S proteasome regulatory subunit S1,26S proteasome subunit p112 |
| 6 | F (V) | RPN3 | polymer | 534 | 61066.5 | 1 | UniProt (O43242) | Homo sapiens (human) | 26S proteasome regulatory subunit RPN3,26S proteasome regulatory subunit S3,Proteasome subunit p58 |
| 7 | G (W) | RPN5 | polymer | 456 | 52979.4 | 1 | UniProt (O00232) | Homo sapiens (human) | 26S proteasome regulatory subunit RPN5,26S proteasome regulatory subunit p55 |
| 8 | H (X) | RPN6 | polymer | 422 | 47526.7 | 1 | UniProt (O00231) | Homo sapiens (human) | 26S proteasome regulatory subunit RPN6,26S proteasome regulatory subunit S9,26S proteasome regulatory subunit p44.5 |
| 9 | I (Y) | RPN7 | polymer | 389 | 45592.3 | 1 | UniProt (Q15008) | Homo sapiens (human) | 26S proteasome regulatory subunit RPN7,26S proteasome regulatory subunit S10,Breast cancer-associated protein SGA-113M,Phosphonoformate immuno-associated protein 4,Proteasome regulatory particle subunit p44S10,p42A |
| 10 | J (Z) | RPN8 | polymer | 324 | 37086.4 | 1 | UniProt (P51665) | Homo sapiens (human) | 26S proteasome regulatory subunit RPN8,26S proteasome regulatory subunit S12,Mov34 protein homolog,Proteasome subunit p40 |
| 11 | K (a) | RPN9 | polymer | 376 | 42995.4 | 1 | UniProt (Q9UNM6) | Homo sapiens (human) | 26S proteasome regulatory subunit RPN9,26S proteasome regulatory subunit S11,26S proteasome regulatory subunit p40.5 |
| 12 | L (b) | RPN10 | polymer | 377 | 40781.6 | 1 | UniProt (P55036) | Homo sapiens (human) | 26S proteasome regulatory subunit RPN10,26S proteasome regulatory subunit S5A,Antisecretory factor 1,ASF,Multiubiquitin chain-binding protein |
| 13 | M (c) | RPN11 | polymer | 310 | 34620.0 | 1 | UniProt (O00487) | Homo sapiens (human) | 26S proteasome regulatory subunit RPN11,26S proteasome-associated PAD1 homolog 1 |
| 14 | N (d) | RPN12 | polymer | 350 | 39667.9 | 1 | UniProt (P48556) | Homo sapiens (human) | 26S proteasome regulatory subunit RPN12,26S proteasome regulatory subunit S14,p31 |
| 15 | O (e) | DSS1 | polymer | 70 | 8284.6 | 1 | UniProt (P60896) | Homo sapiens (human) | 26S proteasome complex subunit DSS1,Deleted in split hand/split foot protein 1,Split hand/foot deleted protein 1,Split hand/foot malformation type 1 protein |
| 16 | P (g) | TXNL1 | polymer | 289 | 32284.2 | 1 | UniProt (O43396) | Homo sapiens (human) | 32 kDa thioredoxin-related protein |
| 17 | Q, S, U (C, D, E) | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | non-polymer | 523.2 | 3 | Chemie (AGS) | |||
| 18 | R, T (C, D) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 19 | V (F) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 20 | W (c) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) PubChem (32051) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 735470.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2111.0 | |
| All* | Total formula weight | 737581.8 |
