9PRA
In Situ Structure of the Human Mitoribosome Large Subunit 39S in Complex with EF-Tu
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (0) | 39S ribosomal protein L32, mitochondrial | polymer | 188 | 21437.8 | 1 | UniProt (Q9BYC8) | Homo sapiens (human) | MRP-L32,Mitochondrial large ribosomal subunit protein bL32m |
| 2 | B (1) | 39S ribosomal protein L33, mitochondrial | polymer | 65 | 7635.2 | 1 | UniProt (O75394) | Homo sapiens (human) | MRP-L33,Mitochondrial large ribosomal subunit protein bL33m |
| 3 | C (2) | 39S ribosomal protein L34, mitochondrial | polymer | 92 | 10183.9 | 1 | UniProt (Q9BQ48) | Homo sapiens (human) | MRP-L34,Mitochondrial large ribosomal subunit protein bL34m |
| 4 | D (3) | 39S ribosomal protein L35, mitochondrial | polymer | 188 | 21558.5 | 1 | UniProt (Q9NZE8) | Homo sapiens (human) | MRP-L35,Mitochondrial large ribosomal subunit protein bL35m |
| 5 | E (4) | 39S ribosomal protein L36, mitochondrial | polymer | 103 | 11809.3 | 1 | UniProt (Q9P0J6) | Homo sapiens (human) | MRP-L36,BRCA1-interacting protein 1,Mitochondrial large ribosomal subunit protein bL36m |
| 6 | F (5) | 39S ribosomal protein L37, mitochondrial | polymer | 423 | 48183.3 | 1 | UniProt (Q9BZE1) | Homo sapiens (human) | MRP-L37,39S ribosomal protein L2,mitochondrial,MRP-L2,Mitochondrial large ribosomal subunit protein mL37 |
| 7 | G (6) | 39S ribosomal protein L38, mitochondrial | polymer | 380 | 44659.4 | 1 | UniProt (Q96DV4) | Homo sapiens (human) | MRP-L38,Mitochondrial large ribosomal subunit protein mL38 |
| 8 | H (7) | 39S ribosomal protein L39, mitochondrial | polymer | 338 | 38764.8 | 1 | UniProt (Q9NYK5) | Homo sapiens (human) | MRP-L39,39S ribosomal protein L5,mitochondrial,MRP-L5,Mitochondrial large ribosomal subunit protein mL39 |
| 9 | I (8) | 39S ribosomal protein L40, mitochondrial | polymer | 206 | 24534.4 | 1 | UniProt (Q9NQ50) | Homo sapiens (human) | MRP-L40,Mitochondrial large ribosomal subunit protein mL40,Nuclear localization signal-containing protein deleted in velocardiofacial syndrome,Up-regulated in metastasis |
| 10 | J (9) | 39S ribosomal protein L41, mitochondrial | polymer | 137 | 15404.7 | 1 | UniProt (Q8IXM3) | Homo sapiens (human) | MRP-L41,39S ribosomal protein L27 homolog,Bcl-2-interacting mitochondrial ribosomal protein L41,Cell proliferation-inducing gene 3 protein,MRP-L27 homolog,Mitochondrial large ribosomal subunit protein mL41 |
| 11 | K (d) | 39S ribosomal protein L45, mitochondrial | polymer | 306 | 35402.9 | 1 | UniProt (Q9BRJ2) | Homo sapiens (human) | MRP-L45,Mitochondrial large ribosomal subunit protein mL45 |
| 12 | L (e) | 39S ribosomal protein L46, mitochondrial | polymer | 279 | 31748.1 | 1 | UniProt (Q9H2W6) | Homo sapiens (human) | MRP-L46,Mitochondrial large ribosomal subunit protein mL46,P2ECSL |
| 13 | M (f) | 39S ribosomal protein L48, mitochondrial | polymer | 212 | 23970.8 | 1 | UniProt (Q96GC5) | Homo sapiens (human) | MRP-L48,Mitochondrial large ribosomal subunit protein mL48 |
| 14 | N (D) | 39S ribosomal protein L2, mitochondrial | polymer | 305 | 33355.9 | 1 | UniProt (Q5T653) | Homo sapiens (human) | MRP-L2,Mitochondrial large ribosomal subunit protein uL2m |
| 15 | O (E) | 39S ribosomal protein L3, mitochondrial | polymer | 348 | 38689.6 | 1 | UniProt (P09001) | Homo sapiens (human) | MRP-L3,Mitochondrial large ribosomal subunit protein uL3m |
| 16 | P (F) | 39S ribosomal protein L4, mitochondrial | polymer | 311 | 34970.2 | 1 | UniProt (Q9BYD3) | Homo sapiens (human) | MRP-L4,Mitochondrial large ribosomal subunit protein uL4m |
| 17 | AB, BB, Q, WA, XA... (G, t, u, v, w...) | 39S ribosomal protein L12, mitochondrial | polymer | 198 | 21378.2 | 7 | UniProt (P52815) | Homo sapiens (human) | MRP-L12,5c5-2,Mitochondrial large ribosomal subunit protein bL12m |
| 18 | R (H) | 39S ribosomal protein L9, mitochondrial | polymer | 267 | 30296.4 | 1 | UniProt (Q9BYD2) | Homo sapiens (human) | MRP-L9,Mitochondrial large ribosomal subunit protein bL9m |
| 19 | S (I) | 39S ribosomal protein L10, mitochondrial | polymer | 261 | 29322.5 | 1 | UniProt (Q7Z7H8) | Homo sapiens (human) | MRP-L10,39S ribosomal protein L8,mitochondrial,MRP-L8,Mitochondrial large ribosomal subunit protein uL10m |
| 20 | T (J) | 39S ribosomal protein L11, mitochondrial | polymer | 192 | 20716.2 | 1 | UniProt (Q9Y3B7) | Homo sapiens (human) | MRP-L11,Mitochondrial large ribosomal subunit protein uL11m |
| 21 | U (K) | Large ribosomal subunit protein uL13m | polymer | 178 | 20617.8 | 1 | UniProt (H2QWN0) | Homo sapiens (human) | 39S ribosomal protein L13,mitochondrial |
| 22 | V (L) | 39S ribosomal protein L14, mitochondrial | polymer | 145 | 15973.7 | 1 | UniProt (Q6P1L8) | Homo sapiens (human) | MRP-L14,39S ribosomal protein L32,mitochondrial,MRP-L32,Mitochondrial large ribosomal subunit protein uL14m |
| 23 | W (M) | 39S ribosomal protein L15, mitochondrial | polymer | 296 | 33473.8 | 1 | UniProt (Q9P015) | Homo sapiens (human) | MRP-L15,Mitochondrial large ribosomal subunit protein uL15m |
| 24 | X (N) | 39S ribosomal protein L16, mitochondrial | polymer | 251 | 28496.3 | 1 | UniProt (Q9NX20) | Homo sapiens (human) | MRP-L16,Mitochondrial large ribosomal subunit protein uL16m |
| 25 | Y (O) | 39S ribosomal protein L17, mitochondrial | polymer | 175 | 20083.3 | 1 | UniProt (Q9NRX2) | Homo sapiens (human) | MRP-L17,LYST-interacting protein 2,Mitochondrial large ribosomal subunit protein bL17m |
| 26 | Z (P) | 39S ribosomal protein L18, mitochondrial | polymer | 180 | 20607.6 | 1 | UniProt (Q9H0U6) | Homo sapiens (human) | MRP-L18,Mitochondrial large ribosomal subunit protein uL18m |
| 27 | AA (Q) | 39S ribosomal protein L19, mitochondrial | polymer | 292 | 33585.0 | 1 | UniProt (P49406) | Homo sapiens (human) | MRP-L19,39S ribosomal protein L15,mitochondrial,MRP-L15,Mitochondrial large ribosomal subunit protein bL19m |
| 28 | BA (R) | 39S ribosomal protein L20, mitochondrial | polymer | 149 | 17479.7 | 1 | UniProt (Q9BYC9) | Homo sapiens (human) | MRP-L20,Mitochondrial large ribosomal subunit protein bL20m |
| 29 | CA (S) | 39S ribosomal protein L21, mitochondrial | polymer | 205 | 22847.7 | 1 | UniProt (Q7Z2W9) | Homo sapiens (human) | MRP-L21,Mitochondrial large ribosomal subunit protein bL21m |
| 30 | DA (T) | 39S ribosomal protein L22, mitochondrial | polymer | 206 | 23683.7 | 1 | UniProt (Q9NWU5) | Homo sapiens (human) | MRP-L22,39S ribosomal protein L25,mitochondrial,MRP-L25,Mitochondrial large ribosomal subunit protein uL22m |
| 31 | EA (U) | 39S ribosomal protein L23, mitochondrial | polymer | 153 | 17807.2 | 1 | UniProt (Q16540) | Homo sapiens (human) | MRP-L23,L23 mitochondrial-related protein,Mitochondrial large ribosomal subunit protein uL23m,Ribosomal protein L23-like |
| 32 | FA (V) | 39S ribosomal protein L24, mitochondrial | polymer | 216 | 24953.9 | 1 | UniProt (Q96A35) | Homo sapiens (human) | MRP-L24,Mitochondrial large ribosomal subunit protein uL24m |
| 33 | GA (W) | 39S ribosomal protein L27, mitochondrial | polymer | 148 | 16102.9 | 1 | UniProt (Q9P0M9) | Homo sapiens (human) | MRP-L27,Mitochondrial large ribosomal subunit protein bL27m |
| 34 | HA (X) | 39S ribosomal protein L28, mitochondrial | polymer | 256 | 30202.9 | 1 | UniProt (Q13084) | Homo sapiens (human) | MRP-L28,Melanoma antigen p15,Melanoma-associated antigen recognized by T-lymphocytes,Mitochondrial large ribosomal subunit protein bL28m |
| 35 | IA (Y) | 39S ribosomal protein L47, mitochondrial | polymer | 250 | 29508.5 | 1 | UniProt (Q9HD33) | Homo sapiens (human) | MRP-L47,Mitochondrial large ribosomal subunit protein uL29m,Nasopharyngeal carcinoma metastasis-related protein 1 |
| 36 | JA (Z) | 39S ribosomal protein L30, mitochondrial | polymer | 161 | 18582.8 | 1 | UniProt (Q8TCC3) | Homo sapiens (human) | MRP-L30,39S ribosomal protein L28,mitochondrial,MRP-L28,Mitochondrial large ribosomal subunit protein uL30m |
| 37 | KA (b) | 39S ribosomal protein L43, mitochondrial | polymer | 215 | 23457.8 | 1 | UniProt (Q8N983) | Homo sapiens (human) | MRP-L43,Mitochondrial large ribosomal subunit protein mL43,Mitochondrial ribosomal protein bMRP36a |
| 38 | LA (g) | 39S ribosomal protein L49, mitochondrial | polymer | 166 | 19225.0 | 1 | UniProt (Q13405) | Homo sapiens (human) | MRP-L49,Mitochondrial large ribosomal subunit protein mL49,Neighbor of FAU,NOF,Protein NOF1 |
| 39 | MA (h) | 39S ribosomal protein L50, mitochondrial | polymer | 158 | 18349.9 | 1 | UniProt (Q8N5N7) | Homo sapiens (human) | MRP-L50,Mitochondrial large ribosomal subunit protein mL50 |
| 40 | NA (i) | 39S ribosomal protein L51, mitochondrial | polymer | 128 | 15125.9 | 1 | UniProt (Q4U2R6) | Homo sapiens (human) | MRP-L51,Mitochondrial large ribosomal subunit protein mL51,bMRP-64,bMRP64 |
| 41 | OA (j) | 39S ribosomal protein L52, mitochondrial | polymer | 123 | 13682.7 | 1 | UniProt (Q86TS9) | Homo sapiens (human) | MRP-L52,Mitochondrial large ribosomal subunit protein mL52 |
| 42 | PA (k) | Large ribosomal subunit protein mL53 | polymer | 112 | 12020.7 | 1 | UniProt (Q96EL3) | Homo sapiens (human) | 39S ribosomal protein L53,mitochondrial,L53mt,MRP-L53 |
| 43 | QA (l) | 39S ribosomal protein L54, mitochondrial | polymer | 138 | 15844.2 | 1 | UniProt (Q6P161) | Homo sapiens (human) | MRP-L54,Mitochondrial large ribosomal subunit protein mL54 |
| 44 | RA (m) | 39S ribosomal protein L55, mitochondrial | polymer | 128 | 15160.4 | 1 | UniProt (Q7Z7F7) | Homo sapiens (human) | MRP-L55,Mitochondrial large ribosomal subunit protein bL31m,Mitochondrial large ribosomal subunit protein mL55 |
| 45 | SA (n) | Nascent polypeptide | polymer | 43 | 3677.5 | 1 | Homo sapiens | ||
| 46 | TA (o) | Ribosomal protein 63, mitochondrial | polymer | 102 | 12292.3 | 1 | UniProt (Q9BQC6) | Homo sapiens (human) | hMRP63,Mitochondrial large ribosomal subunit protein mL63,Mitochondrial ribosomal protein 63,Mitochondrial ribosomal protein L57 |
| 47 | UA (q) | Growth arrest and DNA damage-inducible proteins-interacting protein 1 | polymer | 222 | 25426.9 | 1 | UniProt (Q8TAE8) | Homo sapiens (human) | 39S ribosomal protein L59,mitochondrial,MRP-L59,CKII beta-associating protein,CR6-interacting factor 1,CRIF1,Mitochondrial large ribosomal subunit protein mL64,Papillomavirus L2-interacting nuclear protein 1,PLINP-1,p53-responsive gene 6 protein |
| 48 | VA (r) | 39S ribosomal protein S18a, mitochondrial | polymer | 196 | 22224.1 | 1 | UniProt (Q9NVS2) | Homo sapiens (human) | S18mt-a,39S ribosomal protein S18-3,mitochondrial,MRP-S18-3,Mitochondrial large ribosomal subunit protein bS18a,Mitochondrial large ribosomal subunit protein mL66 |
| 49 | CB (z) | Large ribosomal subunit protein uL1m | polymer | 325 | 36967.7 | 1 | UniProt (Q9BYD6) | Homo sapiens (human) | 39S ribosomal protein L1,mitochondrial,L1mt,MRP-L1 |
| 50 | DB (Ag) | Elongation factor Tu, mitochondrial | polymer | 455 | 49946.9 | 1 | UniProt (P49411) | Homo sapiens (human) | EF-Tu,P43 |
| 51 | EB (A) | 16S mitochondrial rRNA | polymer | 1558 | 499786.4 | 1 | GenBank (2756414513) | Homo sapiens (human) | |
| 52 | FB (c) | 39S ribosomal protein L44, mitochondrial | polymer | 332 | 37583.3 | 1 | UniProt (Q9H9J2) | Homo sapiens (human) | MRP-L44,Mitochondrial large ribosomal subunit protein mL44 |
| 53 | GB (p) | Peptidyl-tRNA hydrolase ICT1, mitochondrial | polymer | 206 | 23674.2 | 1 | UniProt (Q14197) | Homo sapiens (human) | 39S ribosomal protein L58,mitochondrial,MRP-L58,Digestion substraction 1,DS-1,Immature colon carcinoma transcript 1 protein,Mitochondrial large ribosomal subunit protein mL62 |
| 54 | HB (s) | 39S ribosomal protein S30, mitochondrial | polymer | 439 | 50429.6 | 1 | UniProt (Q9NP92) | Homo sapiens (human) | S30mt,Mitochondrial large ribosomal subunit protein mL65,Mitochondrial large ribosomal subunit protein mS30,Programmed cell death protein 9 |
| 55 | IB (OX) | Mitochondrial inner membrane protein OXA1L | polymer | 435 | 48574.6 | 1 | UniProt (Q15070) | Homo sapiens (human) | OXA1Hs,Oxidase assembly 1-like protein,OXA1-like protein |
| 56 | JB (a) | 39S ribosomal protein L42, mitochondrial | polymer | 142 | 16691.2 | 1 | UniProt (Q9Y6G3) | Homo sapiens (human) | MRP-L42,39S ribosomal protein L31,mitochondrial,MRP-L31,Mitochondrial large ribosomal subunit protein mL42 |
| 57 | KB (Ad) | Mitochondrial assembly of ribosomal large subunit protein 1 | polymer | 234 | 26203.1 | 1 | UniProt (Q96EH3) | Homo sapiens (human) | |
| 58 | LB (Ae) | Mitochondrial ribosome and complex I assembly factor AltMIEF1 | polymer | 70 | 8460.8 | 1 | UniProt (L0R8F8) | Homo sapiens (human) | Alternative MIEF1 protein,AltMIEF1,MIEF1 microprotein,MIEF1-MP,alternative transcript upstream of MiD51,AltMiD51 |
| 59 | MB (Af) | Acyl carrier protein, mitochondrial | polymer | 156 | 17774.6 | 1 | UniProt (O14561) | Homo sapiens (human) | ACP,CI-SDAP,NADH-ubiquinone oxidoreductase 9.6 kDa subunit |
| 60 | NB (B) | mitochondrial tRNAVal | polymer | 72 | 22989.8 | 1 | GenBank (1896813692) | Homo sapiens (human) | |
| 61 | OB, QB (0, 4) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 62 | AI, BC, BI, CI, DC... (A, o, 3, 6, D...) | POTASSIUM ION | non-polymer | 39.1 | 36 | Chemie (K) | |||
| 63 | AC, AD, AE, AF, AG... (g, A, D, E, I) | MAGNESIUM ION | non-polymer | 24.3 | 141 | Chemie (MG) | |||
| 64 | CC (r) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 1 | Chemie (FES) | |||
| 65 | EC, FC (A) | SPERMIDINE | non-polymer | 145.2 | 2 | Chemie (SPD) | |||
| 66 | GC (A) | 1,4-DIAMINOBUTANE | non-polymer | 88.2 | 1 | Chemie (PUT) | |||
| 67 | PI (B) | VALINE | non-polymer | 117.1 | 1 | Chemie (VAL) |
Sequence modifications
K: 2 - 178 (UniProt: H2QWN0)
k: 2 - 112 (UniProt: Q96EL3)
A: 1671 - 3231 (GenBank: 2756414513)
| PDB | External Database | Details |
|---|---|---|
| Ace 1 | - | acetylation |
| Tyr 132 | Asp 132 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ace 1 | - | acetylation |
| PDB | External Database | Details |
|---|---|---|
| - | A 2358 | deletion |
| - | C 2359 | deletion |
| - | U 2360 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 66 |
| Total formula weight | 2081867.5 | |
| Non-Polymers* | Number of molecules | 184 |
| Total formula weight | 5637.0 | |
| All* | Total formula weight | 2087504.5 |
