9PPY
CryoEM structure of delta opioid receptor bound to G proteins and met-enkephalin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Delta-type opioid receptor | polymer | 303 | 33663.4 | 1 | UniProt (P41143) | Homo sapiens (human) | D-OR-1,DOR-1 |
| 2 | B (B) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40414.0 | 1 | UniProt (P63096) | Homo sapiens (human) | Adenylate cyclase-inhibiting G alpha protein |
| 3 | C (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37342.8 | 1 | UniProt (P62873) | Homo sapiens (human) | Transducin beta chain 1 |
| 4 | D (D) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) | Homo sapiens (human) | G gamma-I |
| 5 | E (E) | ScFv16 protein | polymer | 251 | 26679.7 | 1 | Mus musculus | ||
| 6 | F (F) | DTY-GLY-GLY-DPN-MET | polymer | 5 | 573.7 | 1 | Homo sapiens |
Sequence modifications
A: 38 - 338 (UniProt: P41143)
B: 1 - 354 (UniProt: P63096)
C: 2 - 340 (UniProt: P62873)
| PDB | External Database | Details |
|---|---|---|
| Gly 36 | - | expression tag |
| Ser 37 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asn 47 | Ser 47 | engineered mutation |
| Ala 203 | Gly 203 | engineered mutation |
| Ala 245 | Glu 245 | engineered mutation |
| Ser 326 | Ala 326 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 146534.8 | |
| All* | Total formula weight | 146534.8 |
