9PN2

Influenza PA-N Endonuclease I38T mutant with compound 3 ((6M)-3-hydroxy-6-[2-(methylsulfanyl)phenyl]-4-oxo-1,4-dihydropyridine-2-carboxylic acid)

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Polymerase acidic protein	polymer	192	22322.4	1	UniProt (C3W5S0)	Influenza A virus (A/California/04/2009(H1N1))	RNA-directed RNA polymerase subunit P2
2	B, C (A)	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
3	D (A)	(6M)-3-hydroxy-6-[2-(methylsulfanyl)phenyl]-4-oxo-1,4-dihydropyridine-2-carboxylic acid	non-polymer		277.3	1	Chemie (A1CI4)
4	E (A)	water	water		18.0	33	Chemie (HOH)

Sequence modifications

A: 1 - 198 (UniProt: C3W5S0)

PDB	External Database	Details
Met -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Ala 0	-	expression tag
Thr 38	Ile 38	engineered mutation
Gly 51	Phe 51	conflict
Gly 52	His 52	conflict
-	Phe 53	deletion
-	Ile 54	deletion
-	Asp 55	deletion
-	Glu 56	deletion
-	Arg 57	deletion
-	Gly 58	deletion
-	Glu 59	deletion
-	Ser 60	deletion
-	Ile 61	deletion
-	Ile 62	deletion
-	Val 63	deletion
-	Glu 64	deletion

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	22322.4
Non-Polymers*	Number of molecules	3
	Total formula weight	387.2
All*	Total formula weight	22709.5

*Water molecules are not included.