9PM6

Cryo-EM structure of modified Zika virus E protein dimer complexed with a neutralizing antibody OZ-D4 Fab

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Envelope protein E	polymer	434	47251.2	2	UniProt (A0A1D6XWI9)	Zika virus
2	C, E (H, C)	OZ-D4 Heavy chain	polymer	227	24403.2	2		Homo sapiens (human)
3	D, F (L, D)	OZ-D4 Light chain	polymer	216	22528.8	2		Homo sapiens (human)

Sequence modifications

A, B: 0 - 405 (UniProt: A0A1D6XWI9)

PDB	External Database	Details
Arg -19	-	expression tag
Ser -18	-	expression tag
Gly -17	-	expression tag
Ser -16	-	expression tag
Gly -15	-	expression tag
Glu -14	-	expression tag
Gln -13	-	expression tag
Lys -12	-	expression tag
Leu -11	-	expression tag
Ile -10	-	expression tag
Ser -9	-	expression tag
Glu -8	-	expression tag
Glu -7	-	expression tag
Asp -6	-	expression tag
Leu -5	-	expression tag
Gly -4	-	expression tag
Gly -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Cys 264	Ala 556	conflict
Gly 406	-	expression tag
Thr 407	-	expression tag
Gly 408	-	expression tag
His 409	-	expression tag
His 410	-	expression tag
His 411	-	expression tag
His 412	-	expression tag
His 413	-	expression tag
His 414	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	188366.5
All*	Total formula weight	188366.5

*Water molecules are not included.