9PKX

Alpha1/Beta Heteromeric Glycine receptor in the presence of 0.200 mM strychnine and 500 nM ivermectin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, D, C, B)	Glycine receptor, alpha 1	polymer	458	52537.6	4	UniProt (B3DHZ5) Pfam (PF02931) Pfam (PF02932)	Danio rerio (zebrafish)
2	E (E)	Glycine receptor beta subunit 2	polymer	591	65820.3	1	UniProt (Q6DC22) Pfam (PF02931) Pfam (PF02932)	Danio rerio (zebrafish)	Glycine receptor,beta b
3	F, I, K, M, N (A, C, B, E)	STRYCHNINE	non-polymer		334.4	5	Chemie (SY9)
4	G, H, J, L, O (A, D, C, B, E)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)

Sequence modifications

A, D, C, B: 1 - 444 (UniProt: B3DHZ5)

PDB	External Database	Details
Leu 445	-	expression tag
Val 446	-	expression tag
Pro 447	-	expression tag
Arg 448	-	expression tag
Gly 449	-	expression tag
Ser 450	-	expression tag
His 451	-	expression tag
His 452	-	expression tag
His 453	-	expression tag
His 454	-	expression tag
His 455	-	expression tag
His 456	-	expression tag
His 457	-	expression tag
His 458	-	expression tag

E: -80 - 494 (UniProt: Q6DC22)

PDB	External Database	Details
Trp -51	-	insertion
Ser -50	-	insertion
His -49	-	insertion
Pro -48	-	insertion
Gln -47	-	insertion
Phe -46	-	insertion
Glu -45	-	insertion
Lys -44	-	insertion
Gly -43	-	insertion
Gly -42	-	insertion
Gly -41	-	insertion
Ser -40	-	insertion
Gly -39	-	insertion
Gly -38	-	insertion
Gly -37	-	insertion
Ser -36	-	insertion
Gly -35	-	insertion
Gly -34	-	insertion
Gly -33	-	insertion
Ser -32	-	insertion
Trp -31	-	insertion
Ser -30	-	insertion
His -29	-	insertion
Pro -28	-	insertion
Gln -27	-	insertion
Phe -26	-	insertion
Glu -25	-	insertion
Lys -24	-	insertion
Gly -23	-	insertion
Gly -22	-	insertion
Gly -21	-	insertion
Ser -20	-	insertion
Gly -19	-	insertion
Gly -18	-	insertion
Gly -17	-	insertion
Ser -16	-	insertion
Gly -15	-	insertion
Gly -14	-	insertion
Gly -13	-	insertion
Ser -12	-	insertion
Trp -11	-	insertion
Ser -10	-	insertion
His -9	-	insertion
Pro -8	-	insertion
Gln -7	-	insertion
Phe -6	-	insertion
Glu -5	-	insertion
Lys -4	-	insertion
Gly -3	-	insertion
Gly -2	-	insertion
Gly -1	-	insertion
Ser 0	-	insertion
Gly 1	-	insertion
Gly 2	-	insertion
Gly 3	-	insertion
Ser 4	-	insertion
Gly 5	-	insertion
Gly 6	-	insertion
Gly 7	-	insertion
Ser 8	-	insertion
Trp 9	-	insertion
Ser 10	-	insertion
His 11	-	insertion
Pro 12	-	insertion
Gln 13	-	insertion
Phe 14	-	insertion
Glu 15	-	insertion
Lys 16	-	insertion
Glu 17	-	insertion
Asn 18	-	insertion
Leu 19	-	insertion
Tyr 20	-	insertion
Phe 21	-	insertion
Gln 22	-	insertion
Gly 23	-	insertion
Glu 24	-	insertion
Lys 25	-	insertion
Ser 26	-	insertion
Ala 27	-	insertion
Lys 28	-	insertion
Lys 29	-	insertion
Glu 495	-	expression tag
Asn 496	-	expression tag
Leu 497	-	expression tag
Tyr 498	-	expression tag
Phe 499	-	expression tag
Gln 500	-	expression tag
Gly 501	-	expression tag
Thr 502	-	expression tag
Glu 503	-	expression tag
Thr 504	-	expression tag
Ser 505	-	expression tag
Gln 506	-	expression tag
Val 507	-	expression tag
Ala 508	-	expression tag
Pro 509	-	expression tag
Ala 510	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	275970.7
Non-Polymers*	Number of molecules	10
	Total formula weight	2778.1
All*	Total formula weight	278748.8

*Water molecules are not included.