9PKV

HU-38 Fab with PRAME pMHC

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	MHC class I antigen	polymer	301	34359.9	1	UniProt (Q8WLS4) Pfam (PF00129) Pfam (PF07654)	Homo sapiens (human)
2	B (K)	VHH antibody	polymer	121	13246.5	1		Lama glama (llama)
3	C (P)	PRAME peptide	polymer	9	994.2	1		Homo sapiens
4	D (H)	HU-38 Heavy Chain	polymer	237	25680.6	1		Mus musculus (mouse)
5	E (B)	Beta-2-microglobulin	polymer	100	11879.4	1	UniProt (P61769) Pfam (PF07654)	Homo sapiens (human)
6	F (L)	HU-38 Light Chain	polymer	214	23287.8	1		Mus musculus (mouse)
7	G, H, I, J, K... (A, K, P, H, B...)	water	water		18.0	191	Chemie (HOH)

Sequence modifications

A: 1 - 276 (UniProt: Q8WLS4)

PDB	External Database	Details
Met 0	-	initiating methionine
Gly 277	-	expression tag
Ser 278	-	expression tag
Gly 279	-	expression tag
Gly 280	-	expression tag
Ser 281	-	expression tag
Gly 282	-	expression tag
Gly 283	-	expression tag
Ser 284	-	expression tag
Ala 285	-	expression tag
Gly 286	-	expression tag
Gly 287	-	expression tag
Gly 288	-	expression tag
Leu 289	-	expression tag
Asn 290	-	expression tag
Asp 291	-	expression tag
Ile 292	-	expression tag
Phe 293	-	expression tag
Glu 294	-	expression tag
Ala 295	-	expression tag
Gln 296	-	expression tag
Lys 297	-	expression tag
Ile 298	-	expression tag
Glu 299	-	expression tag
Trp 300	-	expression tag

B: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	109448.4
All*	Total formula weight	109448.4

*Water molecules are not included.