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9PIW

Crystal structure of a synthetic Fab (1A) in complex with the FRB domain of mTOR

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D
(H, A)
Heavy chainpolymer22623984.82Homo sapiens
2B, E
(L, B)
Light chainpolymer21022687.22Homo sapiens
3C, F
(G, C)
Serine/threonine-protein kinase mTORpolymer9211161.72UniProt (P42345)
Pfam (PF08771)
Homo sapiens (human)FK506-binding protein 12-rapamycin complex-associated protein 1,FKBP12-rapamycin complex-associated protein,Mammalian target of rapamycin,mTOR,Mechanistic target of rapamycin,Rapamycin and FKBP12 target 1,Rapamycin target protein 1,Tyrosine-protein kinase mTOR
4G, H, I, J, K...
(H, L, G, A, B...)
waterwater18.0392Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight115667.4
All*Total formula weight115667.4
*Water molecules are not included.

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PDB entries from 2026-07-22

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