9PI4
Poly dT bound form of Single stranded DNA-binding protein(ICP8) from Herpes simplex virus-1. Mutations: C254S, C455S
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Major DNA-binding protein | polymer | 1128 | 121342.7 | 1 | UniProt (P04296) Pfam (PF00747) | Human alphaherpesvirus 1 (Herpes simplex virus type 1) | |
| 2 | B (G) | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3') | polymer | 8 | 2388.6 | 1 | synthetic construct | ||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) PubChem (32051) | |||
| 4 | D, E (A, G) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A: 9 - 1136 (UniProt: P04296)
| PDB | External Database | Details |
|---|---|---|
| Ala 44 | Ser 44 | variant |
| Asn 224 | Lys 224 | variant |
| Ser 254 | Cys 254 | engineered mutation |
| Pro 306 | Ala 306 | variant |
| Cys 348 | Phe 348 | conflict |
| Ser 455 | Cys 455 | engineered mutation |
| Gly 475 | Ala 475 | variant |
| Asn 1039 | Ser 1039 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 123731.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 123796.7 |
