9PH8
Crystal structure of SARS-CoV-2 nsp14 with SAM bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Guanine-N7 methyltransferase nsp14 | polymer | 531 | 60232.8 | 2 | UniProt (P0DTD1) Pfam (PF06471) | Severe acute respiratory syndrome coronavirus 2 | Non-structural protein 14,nsp14,Proofreading exoribonuclease nsp14,ExoN |
| 2 | C, I (A, B) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) | |||
| 3 | D, E, F, G, J... (A, B) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) PubChem (32051) | |||
| 4 | H (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) PubChem (27854) | |||
| 5 | N, O (A, B) | water | water | 18.0 | 21 | Chemie (HOH) |
Sequence modifications
A, B: 25 - 551 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ser 21 | - | expression tag |
| Asn 22 | - | expression tag |
| Gly 23 | - | expression tag |
| Ser 24 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 120465.6 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1375.1 | |
| All* | Total formula weight | 121840.7 |
