9PGX
Crystal structure of STEAP2 N-domain soaked with NADP+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Metalloreductase STEAP2 | polymer | 182 | 20266.3 | 1 | UniProt (Q8NFT2) Pfam (PF03807) | Homo sapiens (human) | Prostate cancer-associated protein 1,Protein up-regulated in metastatic prostate cancer,PUMPCn,Six-transmembrane epithelial antigen of prostate 2,SixTransMembrane protein of prostate 1 |
| 2 | B, C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 3 | D (A) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 4 | E, F, G, H (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | I (A) | water | water | 18.0 | 207 | Chemie (HOH) |
Sequence modifications
A: 30 - 208 (UniProt: Q8NFT2)
| PDB | External Database | Details |
|---|---|---|
| Gly 27 | - | expression tag |
| His 28 | - | expression tag |
| Met 29 | - | expression tag |
| Ser 65 | Phe 65 | engineered mutation |
| Ser 69 | Phe 69 | engineered mutation |
| Ser 102 | Trp 102 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20266.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1253.8 | |
| All* | Total formula weight | 21520.1 |
